Leukaemia cutis during acute aleukaemic myeloid leukaemia in a two-month-old infant

Annales de dermatologie et de vénéréologie
P PlantinC Berthou

Abstract

Congenital cutaneous leukaemia is rare. A two-month-old girl presented bluish cutaneous macules of the trunk, histological examination of which suggested acute myeloid leukaemia (LAM B 5). The blood picture was negative for circulating tumour cells and the outcome under chemotherapy was favourable at one year of follow-up. The prognosis of congenital leukaemia is serious. Aleukaemic congenital leukaemia is seen occasionally but is rare. The existence of multiple cutaneous tumours in newborn infants raises the possibility of TORCH infection and of other malignant tumours such as nephroblastoma or neuroblastoma.

References

Jan 24, 2006·Journal of the American Academy of Dermatology·Inga Hofmann ZhangMignon L Loh

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