Leukemia incidence following primary breast carcinoma treatment

Cancer
Henry G KaplanMary Atwood

Abstract

The results of randomized clinical trials have suggested that after receiving radiotherapy and/or chemotherapy, patients with primary breast carcinoma have an increased risk of developing leukemia. In the current study, the authors set out to assess the reported association between breast carcinoma treatment and leukemia risk. A registry of all patients with breast carcinoma who were treated at a community-based institution since 1989 (updated annually for recurrence and/or vital status) was linked to the National Cancer Institute Surveillance, Epidemiology, and End Results database to confirm complete ascertainment of leukemia cases occurring within this registry population. Incidence rates were calculated for women who were treated for primary Stage 0-III breast carcinoma and had a follow-up duration of > or = 24 months (n = 2866). Patients who did not undergo surgery (n = 5), patients for whom chemotherapy records were incomplete or who received nonstandard chemotherapy regimens (n = 69), patients who underwent stem cell transplantation (n = 83), and patients who were lost to follow-up or who had unknown disease status at follow-up (n = 81) were excluded from the analysis (total, n = 238). Among patients diagnosed with breas...Continue Reading

References

Sep 1, 1992·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J Pedersen-BjergaardP Dombernowsky
Jul 5, 1992·The New England Journal of Medicine·R E CurtisR N Hoover
Sep 1, 1986·Annals of Internal Medicine·M H GreeneJ D Boice
Jan 1, 1985·Breast Cancer Research and Treatment·G BonadonnaU Veronesi
Dec 1, 1985·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·B FisherA Brown
Jul 1, 1995·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M S TallmanP H Wiernik
Oct 1, 1994·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·S E RivkinC K Osborne
Apr 1, 1996·Hematology/oncology Clinics of North America·M J Thirman, R A Larson
Feb 1, 1997·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·T DemirerW I Bensinger
Mar 21, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·M J LaughlinJ J Vredenburgh
Jul 17, 1998·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·J H FettingM D Abeloff
Aug 2, 2000·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·G ChaplainC Bonithon-Kopp
Jan 30, 2002·CA: a Cancer Journal for Clinicians·Ahmedin JemalMichael Thun
Nov 7, 2002·Annals of Oncology : Official Journal of the European Society for Medical Oncology·A Foss AbrahamsenS Kvaløy
Mar 1, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·James O ArmitageStewart Kroll
Mar 29, 2003·Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology·Roy E SmithUNKNOWN National Surgical Adjuvant Breast and Bowel Project Experience

❮ Previous
Next ❯

Citations

Jan 16, 2007·Breast Cancer Research and Treatment·Regan A HowardLois B Travis
Jan 6, 2011·Journal of Postgraduate Medicine·H ChandraV P Pathak
Mar 2, 2010·Women's Health·Francesco Lo-CocoSafaa M Ramadan
Aug 20, 2011·Leukemia & Lymphoma·Sara Abu-GhanemDavid B Geffen
Feb 7, 2006·International Journal of Radiation Oncology, Biology, Physics·Tony C S WooKathleen Pritchard
Jan 3, 2006·The Breast : Official Journal of the European Society of Mastology·R RenellaC Bouchardy
Jan 15, 2008·International Journal of Hematology·Hüseyin Engin, Ayla Gökmen Aköz
Jan 11, 2017·Journal of Medical Case Reports·Choukri Elm'hadiMohammed Ichou
May 21, 2005·Annals of Oncology : Official Journal of the European Society for Medical Oncology·M CamponeP Fumoleau

❮ Previous
Next ❯

Related Concepts

Related Feeds

B-Cell Leukemia (Keystone)

B-cell leukemia includes various types of lymphoid leukemia that affect B cells. Here is the latest research on B-cell leukemia.

Blood And Marrow Transplantation

The use of hematopoietic stem cell transplantation or blood and marrow transplantation (bmt) is on the increase worldwide. BMT is used to replace damaged or destroyed bone marrow with healthy bone marrow stem cells. Here is the latest research on bone and marrow transplantation.

AML: Role of LSD1 by CRISPR (Keystone)

Find the latest rersearrch on the ability of CRISPR-Cas9 mutagenesis to profile the interactions between lysine-specific histone demethylase 1 (LSD1) and chemical inhibitors in the context of acute myeloid leukemia (AML) here.

Acute Myeloid Leukemia

Acute myeloid leukemia (AML) is a clinically and genetically heterogeneous disease with approximately 20,000 cases per year in the United States. AML also accounts for 15-20% of all childhood acute leukemias, while it is responsible for more than half of the leukemic deaths in these patients. Here is the latest research on this disease.

Related Papers

Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Roy E SmithNational Surgical Adjuvant Breast and Bowel Project Experience
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Debra A PattSharon H Giordano
Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology
Michael CrumpK I Pritchard
© 2021 Meta ULC. All rights reserved