Leukocyte-related parameters in older adults with metabolic syndrome.

Endocrine
Xue-Jiao YangChen-Wei Pan

Abstract

We aimed to examine the association between leukocyte-related parameters and the risk of metabolic syndrome (MetS) in community-dwelling older Chinese adults, with a special focus on assessing the diagnostic ability of leukocyte-related parameters in detecting MetS and the potential interaction effect of sex in the leukocyte-MetS relationship. Study sample was from the Weitang Geriatric Diseases Study, which included 4579 individuals aged 60 years or above. MetS was diagnosed based on the Adult Treatment Panel III criteria. Leukocyte-related parameters were assessed using an automated hematology analyzer. The adjusted odds ratio (95% confidence interval (CI)) of MetS for the highest quartile of leukocyte-related parameters (leukocyte, lymphocyte, neutrophil, monocyte, eosinophil, and basophil), when compared with the lowest quartile were 2.87 (2.30, 3.59), 2.69 (2.15, 3.36), 2.09 (1.67, 2.62), 2.12 (1.71, 2.64), 1.62 (1.31, 2.00), and 1.36 (1.11, 1.65), respectively. Adding leukocyte, lymphocyte, monocyte, and neutrophil to a model containing conventional risk factors improved risk prediction for MetS. Furthermore, significant interactions between leukocyte, monocyte, neutrophil, and sex on MetS were observed (all P value for i...Continue Reading

References

May 1, 1994·Annals of Epidemiology·J Schwartz, S T Weiss
Dec 17, 1997·The Journal of Clinical Endocrinology and Metabolism·V Mohamed-AliS W Coppack
May 23, 2001·JAMA : the Journal of the American Medical Association·UNKNOWN Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults
May 13, 2003·Proceedings of the National Academy of Sciences of the United States of America·Marisa BenagianoGianfranco Del Prete
Oct 2, 2004·Circulation Journal : Official Journal of the Japanese Circulation Society·Nobue NagasawaHideaki Toyoshima
Apr 20, 2005·Lancet·Robert H EckelPaul Z Zimmet
May 17, 2005·Journal of the American College of Cardiology·Benjamin D HorneUNKNOWN Intermountain Heart Collaborative Study Group
Dec 7, 2005·The Journal of Clinical Hypertension·Ammar JesriBrent M Egan
Jan 6, 2006·Journal of Atherosclerosis and Thrombosis·Paul ZimmetJonathan Shaw
Mar 18, 2006·Endocrine Journal·Jeong A KimSeon Mee Kim
Dec 15, 2006·Nature·Gökhan S Hotamisligil
Aug 9, 2008·The American Journal of Pathology·DeLisa FairweatherNoel R Rose
Sep 9, 2008·Endocrinology and Metabolism Clinics of North America·Babak RazaniClay F Semenkovich
Aug 1, 2009·Arteriosclerosis, Thrombosis, and Vascular Biology·Carine DuffautAnne Bouloumié
Aug 20, 2009·Cardiology in Review·Emmanuel S AndroulakisChristodoulos Stefanadis
Dec 24, 2009·The Journal of Biological Chemistry·Koji OhashiKenneth Walsh
Nov 2, 2011·Internal Medicine·Keiichi OdagiriChinori Kurata
Dec 27, 2011·Thrombosis Research·Bjarne Osterud
Feb 23, 2012·Menopause : the Journal of the North American Menopause Society·Jung-Ha KimDuk-Chul Lee
Sep 11, 2012·Diabetes Care·Gilad TwigAmir Tirosh
Nov 26, 2015·Scientific Reports·Chen-Wei PanPei Wang
Jan 5, 2017·Asia Pacific Journal of Clinical Nutrition·Hong YangDuo Li
Dec 10, 2017·Archives of Medical Research·Ki-Chul SungAlice Liu
Jan 8, 2020·International Journal of Environmental Research and Public Health·Eleonora PalellaMarta Greco

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.