PMID: 7034448Jan 1, 1981Paper

Leukoplakia-like lesions developing in patients with oral discoid lupus erythematosus

Acta Odontologica Scandinavica
M SchiødtC J Smith

Abstract

In a long-term follow-up of 52 patients with oral lesions of discoid lupus erythematosus (DLE) 8 patients showed a gradual transition of the typical DLE lesions to lesions which closely resemble leukoplakia. Histopathologically and immunopathologically the leukoplakia-like lesions generally showed features similar to those in leukoplakias not preceded by DLE. Ultrastructurally, the leukoplakia-like lesions showed the presence of cytoplasmic tubular structures in vascular endothelium in two out of three patients examined. The leukoplakia-like stage is considered to be an inactive or scar-like stage, which may be the mucous membrane counterpart of the atrophic scars following DLE lesions of the skin. A primary examination of a DLE patient presenting oral lesions at the leukoplakia-like stage may result in an incorrect diagnosis. Therefore, when investigating patients with leukoplakias, they should be questioned on previous or present skin lesions as well as symptoms of systemic lupus erythematosus.

References

Apr 1, 1978·International Journal of Oral Surgery·M SchiödtB Hentzer
Nov 1, 1978·Community Dentistry and Oral Epidemiology·J J Pindborg
Oct 1, 1976·International Journal of Oral Surgery·M Schiödt, J J Pindborg
Jun 1, 1981·Oral Surgery, Oral Medicine, and Oral Pathology·M SchiødtS Ullman
Oct 1, 1964·Acta Odontologica Scandinavica·J O ANDREASEN, H E POULSEN

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Citations

Mar 1, 1984·Oral Surgery, Oral Medicine, and Oral Pathology·M Schiødt
Apr 1, 1984·International Journal of Oral Surgery·M Schiødt
Sep 14, 2007·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Jeaneth López-LabadyMagdalena Mata de Henning
Jan 1, 1984·Oral Surgery, Oral Medicine, and Oral Pathology·M Schiødt, J J Pindborg
May 10, 2017·American Journal of Clinical Dermatology·Pongsawat RodsawardDirekrit Chiewchengchol

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