Leukotriene inhibitors for bronchiolitis in infants and young children

The Cochrane Database of Systematic Reviews
Fang LiuRufu Xu

Abstract

Bronchiolitis is an acute inflammatory illness of the bronchioles common among infants and young children. It is often caused by the respiratory syncytial virus (RSV). Management of bronchiolitis varies between clinicians, reflecting the lack of evidence for a specific treatment approach. The leukotriene pathway has been reported to be involved in the pathogenesis of bronchiolitis. Leukotriene inhibitors such as montelukast have been used in infants and young children with bronchiolitis. However, the results from limited randomised controlled trials (RCTs) are controversial and necessitate a thorough evaluation of their efficacy for bronchiolitis in infants and young children. To assess the efficacy and safety of leukotriene inhibitors for bronchiolitis in infants and young children. We searched CENTRAL (2014, Issue 5), MEDLINE (1946 to April week 4, 2014), EMBASE (1974 to May 2014), CINAHL (1981 to May 2014), LILACS (1982 to May 2014), Web of Science (1985 to May 2014), WHO ICTRP and ClinicalTrials.gov (6 May 2014). RCTs comparing leukotriene inhibitors versus placebo or another intervention in infants and young children under two years of age diagnosed with bronchiolitis. Our primary outcomes were length of hospital stay and ...Continue Reading

References

Oct 27, 1999·JAMA : the Journal of the American Medical Association·D K ShayL J Anderson
Oct 31, 2002·American Journal of Respiratory and Critical Care Medicine·Hans Bisgaard, UNKNOWN Study Group on Montelukast and Respiratory Syncytial Virus
Nov 26, 2003·The Journal of Infectious Diseases·Joanne M LangleyElaine E L Wang
Apr 13, 2005·Pediatric Emergency Care·Jonathan M MansbachCarlos A Camargo
Aug 18, 2005·Pediatric Pulmonology·Giovanni PiedimonteRenato Cutrera
May 19, 2006·Journal of Clinical Pharmacology·Barbara KnorrGregory Kearns
Jun 21, 2006·Psychological Methods·Tania B Huedo-MedinaJuan Botella
Apr 5, 2007·Drug and Therapeutics Bulletin
Feb 26, 2008·Journal of Clinical Pharmacology·Gregory L KearnsTheodore F Reiss
Jun 28, 2008·American Journal of Respiratory and Critical Care Medicine·Hans BisgaardBarbara A Knorr
Jul 16, 2008·Clinical Microbiology Reviews·Shyam S Mohapatra, Sandhya Boyapalle
Jul 24, 2008·Pulmonary Pharmacology & Therapeutics·Elisabeth M W KooiEric J Duiverman
Nov 1, 2008·The Journal of Allergy and Clinical Immunology·Leonard B BacharierUNKNOWN CARE Network
Nov 26, 2008·Paediatric Respiratory Reviews·Clare Halfhide, Rosalind L Smyth
Jan 24, 2009·The New England Journal of Medicine·Andrew Bush
Mar 28, 2009·The Journal of Pediatrics·Katherine Rivera-SpoljaricUNKNOWN Childhood Asthma Research and Education (CARE) Network
Feb 23, 2010·The Journal of Pediatrics·Chang-Keun KimYoung Yull Koh
Mar 27, 2010·Respirology : Official Journal of the Asian Pacific Society of Respirology·Douglas C CowanD Robin Taylor
Apr 22, 2010·Allergy and Asthma Proceedings·Magdy ZedanAhmed Settin
Jan 22, 2011·Respiratory Medicine·Henrik WidegrenLennart Greiff
Jun 17, 2011·The Cochrane Database of Systematic Reviews·Lisa HartlingRicardo M Fernandes
Nov 8, 2011·Journal of Pediatric Nursing·Suzanne E Zentz
Jan 14, 2012·European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology·D HervásJ A Hervás
Oct 13, 2012·The European Respiratory Journal·Anna S PelkonenMika J Mäkelä
Jun 5, 2013·The Cochrane Database of Systematic Reviews·Ricardo M FernandesLisa Hartling
Aug 1, 2013·The Cochrane Database of Systematic Reviews·Linjie ZhangTerry P Klassen
Oct 1, 2010·Saudi Pharmaceutical Journal : SPJ : the Official Publication of the Saudi Pharmaceutical Society·Fadyia Y Al-Hamdani
Oct 15, 2013·Pediatric Allergy and Immunology : Official Publication of the European Society of Pediatric Allergy and Immunology·Wan-Sheng PengEn-Mei Liu
Jun 18, 2014·The Cochrane Database of Systematic Reviews·Anne M Gadomski, Melissa B Scribani
Oct 11, 2014·The Cochrane Database of Systematic Reviews·Rebecca FarleyChris B Del Mar

❮ Previous
Next ❯

Citations

May 17, 2018·European Journal of Pediatrics·Minna MecklinMatti Korppi
Nov 2, 2018·Expert Review of Anti-infective Therapy·Marwa Ghazaly, Simon Nadel
Mar 1, 2019·Japanese Journal of Infectious Diseases·Akinobu TaniguchiUNKNOWN Nagoya Collaborative Clinical Research Team
Feb 22, 2018·Thorax·Steve Cunningham, Hilary Pinnock
Jul 7, 2020·International Journal of Molecular Medicine·Ioannis N MammasDemetrios A Spandidos
Jan 24, 2017·Pediatric Pulmonology·Shu-Ling ChongJan Hau Lee

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

The Cochrane Database of Systematic Reviews
Kana R Jat, Joseph L Mathew
The Cochrane Database of Systematic Reviews
Ajibola A AwotiwonCharles I Okwundu
The Cochrane Database of Systematic Reviews
David KingGeoffrey K P Spurling
The Cochrane Database of Systematic Reviews
Alison HaywoodJanet R Hardy
The Cochrane Database of Systematic Reviews
Jia LiuEwan D McNicol
© 2021 Meta ULC. All rights reserved