May 13, 1976

Levamisole, a chemically defined substance with immunostimulating potential--a review

Fortschritte der Medizin
G F Staber

Abstract

In contrast to immunosuppression, immunostimulation is still at an early stage of development. Levamisole is the first chemically defined substance with immunostimulating potential which can be applied systemically. After a short consideration of the chemistry and pharmacology of Levamisole, its effect in different animal experimental models of humoral and cell-mediated immunity are discussed in detail. Moreover, the following review deals with the influence of Levamisole on several immunological parameters in man. Finally, the therapeutical results achieved up to now by different clinical indications are reported.

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Mentioned in this Paper

Antibiotic Resistance, Microbial
Variolation
Lymphoid Cells
Graft Vs Host Reaction
Antibody Formation
Lymphocyte Activation
Phagocytosis
Solaskil
Cricetus
Cellular Immune Response

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