Levels and changes in body mass index decomposed into fat and fat-free mass index: relation to long-term all-cause mortality in the general population.

International Journal of Obesity : Journal of the International Association for the Study of Obesity
Thorkild I A SørensenBerit L Heitmann

Abstract

In the general population, body mass index (BMI = weight (kg)/(height (m))2) shows a U-shaped relation to mortality, which is attributable to a combination of an inverse association with fat-free mass index (FFMI) and a direct association with fat mass index (FMI). However, preceding changes in body composition related to diseases, health behaviors, or social conditions that are also influencing later mortality may confound these associations. To examine associations of FFMI and FMI, adjusted for preceding changes in FFMI and FMI over a 6 years period, with all-cause mortality in a healthy general population. The study population was a random subset of adult Danes, participating in the Danish MONICA project; 989 men and 962 women, born 1922, 1932, 1942, and 1952, and examined in 1987-88 and 1993-94. They had no known major co-morbidities until start of follow-up in 1993-94, and were followed up for 18 years. Measures included height, weight, and bio-impedance, from which BMI, FFMI, and FMI were calculated, and information on educational level, smoking, alcohol drinking, leisure-time physical activity, which were obtained by questionnaires. We analyzed the relation between body composition and all-cause mortality by Cox proporti...Continue Reading

References

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Citations

Jan 14, 2021·The American Journal of Clinical Nutrition·Anja M SedlmeierMichael F Leitzmann
Aug 17, 2021·Aging Clinical and Experimental Research·Francesca RemelliUNKNOWN GLISTEN Group Investigators
Aug 29, 2021·Journal of Aging and Physical Activity·Marina ChristofolettiThiago S Matias

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