Levels of anti-A and anti-B in commercial immune globulins

Transfusion
J M GordonJ S Finlayson

Abstract

Samples from 168 lots of immune serum globulin, tetanus immune globulin, and Rho (D) immune globulin produced by seven American manufacturers during the period 1973-1977 were analyzed for anti-A and anti-B content by saline and antiglobulin titration. There was appreciable variation among manufacturers, but between 1973 and 1975 all products showed a significant decrease in alloantibody titer. This trend did not continue during the interval 1975-1977; the titers of most manufacturers' products remained near the 1975 level. The anti-A titer of a given product was approximately one dilution higher than the anti-B; both titers were usually increased by anti-human serum, though this occurred more often in the case of anti-B.

Citations

Sep 27, 1980·Lancet·B C McLeodM I Pierce
Oct 7, 2009·American Journal of Hematology·David J GordonJill L O de Jong
Sep 26, 2003·Transfusion·Irina Knezevic-Maramica, Margot S Kruskall
Oct 30, 2013·Transfusion Medicine·M J DesboroughS A Misbah
Feb 17, 2005·Biologicals : Journal of the International Association of Biological Standardization·Christoph BuchtaPaul Höcker
Feb 24, 2006·Biologicals : Journal of the International Association of Biological Standardization·Guillermo LeónJosé María Gutiérrez
Oct 26, 2013·Autoimmunity Reviews·Karmtej SinghM Eric Gershwin
Sep 1, 1997·Muscle & Nerve·J R WilsonM Fisher

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.