Levels of soluble Fas in patients with myocarditis, heart failure of unknown origin, and in healthy volunteers

The American Journal of Cardiology
T ToyozakiH Ohwada

Abstract

This study showed that serum levels of sFas were elevated in patients with myocarditis, and that this elevation was correlated with sIL-2R level as a marker of T-cell activation. Therefore, sFas levels may be associated with T-cell activation in patients with myocarditis, and elevation of sFas may inhibit apoptosis in activated T cells, leading to persistent cell-mediated destruction of myocytes in myocarditis.

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