Leveraging Latent Dirichlet Allocation in processing free-text personal goals among patients undergoing bladder cancer surgery

Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation
Yuelin LiBernard Bochner

Abstract

As we begin to leverage Big Data in health care settings and particularly in assessing patient-reported outcomes, there is a need for novel analytics to address unique challenges. One such challenge is in coding transcribed interview data, typically free-text entries of statements made during a face-to-face interview. Latent Dirichlet Allocation (LDA) offers statistical rigor and consistency in automating the interpretation of patients' expressed concerns and coping strategies. LDA was applied to interview data collected as part of a prospective, longitudinal study of QOL in N = 211 patients undergoing radical cystectomy and urinary diversion for bladder cancer. LDA analyzed personal goal statements to extract the latent topics and themes, stratified by time, and on things patients wanted to accomplish and prevent. Model comparison metrics determined the number of topics to extract. LDA extracted seven latent topics. Prior to surgery, patients' priorities were primarily in cancer surgery and recovery. Six months after the surgery, they were replaced by goals on regaining a sense of normalcy, to resume work, to enjoy life more fully, and to appreciate friends and family more. LDA model parameters showed changing priorities, e.g....Continue Reading

References

Jan 1, 1983·Cancer Chemotherapy and Pharmacology·G H Friedell
Jul 10, 1999·Social Science & Medicine·M A Sprangers, C E Schwartz
Aug 19, 1999·Journal of the National Cancer Institute
Feb 12, 2004·Proceedings of the National Academy of Sciences of the United States of America·Thomas L Griffiths, Mark Steyvers
Mar 17, 2004·Health and Quality of Life Outcomes·Bruce D Rapkin, Carolyn E Schwartz
Jun 11, 2014·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·A S AliB K Somani
Sep 8, 2015·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Bruce D Rapkin, Carolyn E Schwartz
Dec 2, 2015·European Journal of Surgical Oncology : the Journal of the European Society of Surgical Oncology and the British Association of Surgical Oncology·M A CerrutoW Artibani
Dec 19, 2016·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Carolyn E SchwartzBruce D Rapkin
Mar 3, 2018·Journal of Pain and Symptom Management·Alexander W ForsythCharlotta Lindvall

❮ Previous
Next ❯

Citations

Mar 7, 2020·Current Opinion in Urology·Nima Almassi, Bernard H Bochner
Jun 21, 2019·International Journal of Environmental Research and Public Health·Bach Xuan TranRoger C M Ho
Mar 21, 2020·International Journal of Environmental Research and Public Health·Giang Thu VuCyrus S H Ho
Apr 30, 2020·Quality of Life Research : an International Journal of Quality of Life Aspects of Treatment, Care and Rehabilitation·Bach Xuan TranRoger C M Ho
Nov 7, 2019·International Journal of Environmental Research and Public Health·Bach Xuan TranRoger C M Ho
May 23, 2020·International Journal of Environmental Research and Public Health·Hai Thanh PhanRoger C M Ho
May 6, 2020·International Journal of Environmental Research and Public Health·Giap Van VuCyrus S H Ho
Apr 28, 2021·BMC Cancer·Juan Francisco Ortega-MoránFrancisco M Sánchez-Margallo
Jul 2, 2021·BMJ Health & Care Informatics·Paul FairieMaria J Santana
Mar 10, 2020·Complementary Therapies in Medicine·Bach Xuan TranRoger C M Ho
Mar 3, 2020·Dementia and Geriatric Cognitive Disorders·Chi Linh HoangRoger C M Ho

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.