Levetiracetam-associated loss of libido and anhedonia

Epilepsy & Behavior : E&B
Rocco S CalabròPlacido Bramanti

Abstract

The relationship between the older antiepileptic drugs (AEDs) and sexual dysfunction has long been known and it is likely to be related to sexual hormonal changes. Instead, rare reports on sexual disorders related to new AEDs suggest the possibility of complex and poorly understood mechanisms, mainly involving central nervous system neurotransmitters such as glutamate, serotonin, and dopamine. Herein, we describe two young men with epilepsy who experienced severe loss of libido and anhedonia after levetiracetam intake.

References

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Feb 5, 2009·Epilepsy & Behavior : E&B·Rocco Salvatore CalabròEdoardo Ferlazzo
May 21, 2009·The Journal of Sexual Medicine·James G Pfaus
Jan 22, 2010·Epilepsy & Behavior : E&B·Rocco Salvatore CalabròPlacido Bramanti
Jun 24, 2010·Pharmacology, Biochemistry, and Behavior·Eiki TakahashiChitoshi Itakura
Jul 7, 2010·Neuroscience and Biobehavioral Reviews·Michael T Treadway, David H Zald
Aug 31, 2010·Epilepsy & Behavior : E&B·Rocco Salvatore Calabrò, Placido Bramanti
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Jun 10, 2011·Expert Review of Neurotherapeutics·Rocco Salvatore CalabròPlacido Bramanti

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Citations

Nov 13, 2015·Expert Opinion on Drug Safety·Yong Yang, Xuefeng Wang
May 28, 2013·Archives of Psychiatric Nursing·Nancy Ho, Marilyn Sommers
Jan 24, 2013·Seizure : the Journal of the British Epilepsy Association·Rocco Salvatore Calabrò, Placido Bramanti
Oct 16, 2015·Epilepsy & Behavior : E&B·Kenneth R KaufmanDavid Delatte
Jul 25, 2017·Expert Opinion on Pharmacotherapy·Jasmina R MilovanovićMarina Kostić

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