Levobupivacaine 0.2% or 0.125% for continuous sciatic nerve block: a prospective, randomized, double-blind comparison with 0.2% ropivacaine.

Anesthesia and Analgesia
Andrea CasatiPaola Rivoltini

Abstract

In 60 patients receiving elective hallux valgus repair, we compared the efficacy of continuous popliteal sciatic nerve block produced with 0.2% ropivacaine (n = 20), 0.2% levobupivacaine (n = 20), or 0.125% levobupivacaine (n = 20) infused with a patient-controlled system starting 3 h after a 30-mL bolus of the 0.5% concentration of the study drug and for 48 h (baseline infusion rate, 6 mL/h; incremental dose, 2 mL; lockout time, 15 min; maximum incremental doses per hour, 3). No differences were reported in the intraoperative efficacy of the nerve block. The degree of pain was similar in the three groups throughout the study period, both at rest and during motion. Total consumption of local anesthetic solution during the first 24 h was 148 mL (range, 144-228 mL) with 0.2% ropivacaine, 150 mL (range, 144-200 mL) with 0.2% levobupivacaine, and 148 mL (range, 144-164 mL) with 0.125% levobupivacaine (P = 0.59). The volume of local anesthetic consumed during the second postoperative day was 150 mL (range, 144-164 mL) with 0.2% ropivacaine, 154 mL (range, 144-176 mL) with 0.2% levobupivacaine, and 151 mL (range, 144-216 mL) with 0.125% levobupivacaine (P = 0.14). A smaller proportion of patients receiving 0.2% levobupivacaine showed...Continue Reading

References

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Citations

Dec 13, 2005·Der Anaesthesist·B Urbanek, S Kapral
May 13, 2014·Best Practice & Research. Clinical Anaesthesiology·Christopher K MerrittRichard D Urman
Aug 13, 2009·Pain Medicine : the Official Journal of the American Academy of Pain Medicine·Alexander StojadinovicChester C Buckenmaier
Jun 22, 2005·Best Practice & Research. Clinical Anaesthesiology·Andrea Casati, Marta Putzu
Jul 11, 2009·Foot & Ankle International·Alberto Siclari, Vito Decantis
Aug 24, 2010·Foot & Ankle International·Christopher J Pearce, Paul D Hamilton
Mar 15, 2006·Current Opinion in Anaesthesiology·Paolo Grossi, Massimo Allegri
Dec 22, 2005·Anesthesia and Analgesia·Jaime RodríguezJulián Alvarez
Aug 9, 2011·Anesthesia and Analgesia·Brian M Ilfeld
Oct 8, 2020·Current Opinion in Anaesthesiology·Neel DesaiEric Albrecht

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