Levofloxacin in veterinary medicine: a literature review.

Research in Veterinary Science
Andrejs SitovsMario Giorgi

Abstract

A potent third-generation antimicrobial fluoroquinolone drug, levofloxacin was introduced into human clinical practice in 1993. Levofloxacin is also used in veterinary medicine, however its use is limited: it is completely banned for veterinary use in the EU, and used extralabel in only companion animals in the USA. Since its introduction to clinical practice, many studies have been published on levofloxacin in animal species, including pharmacokinetic studies, tissue drug depletion, efficacy, and animal microbial isolate susceptibility to levofloxacin. This literature overview highlights the most clinically relevant and scientifically important levofloxacin studies linked to the field of veterinary medicine.

References

Feb 1, 1997·Clinical Pharmacokinetics·D N Fish, A T Chow
Apr 28, 2001·Pharmacology, Biochemistry, and Behavior·B F ErdenN Gacar
May 1, 2001·The Journal of Antimicrobial Chemotherapy·C J DestacheA K Dash
Sep 3, 2002·Research in Veterinary Science·P L ToutainA Bousquet-Mélou
Jul 2, 2003·American Journal of Ophthalmology·Tulaya TungsiripatPeter J McDonnell
Oct 29, 2004·The Journal of Antimicrobial Chemotherapy·F M ThibaultJ-D Cavallo
Dec 17, 2004·Journal of Veterinary Pharmacology and Therapeutics·Q A McKellarD G Jones
Jul 30, 2005·Journal of Veterinary Pharmacology and Therapeutics·G A AlbarellosM F Landoni
Jul 26, 2006·Xenobiotica; the Fate of Foreign Compounds in Biological Systems·A HemeryckM F Kelley
Feb 3, 2007·Journal of Clinical Microbiology·Takashi SasakiKeiichi Hiramatsu
Feb 8, 2007·Emerging Infectious Diseases·Alexander Rodriguez-PalaciosJ Scott Weese
Jun 5, 2007·American Journal of Veterinary Research·Eric C LedbetterJanet M Scarlett
Nov 13, 2008·Journal of Veterinary Pharmacology and Therapeutics·A GoudahA M Abd El-Aty
Jan 24, 2009·Journal of Veterinary Pharmacology and Therapeutics·A Goudah, K Abo-El-Sooud
Jul 3, 2009·Veterinary Research Communications·Santosh KumarBirendra K Roy
Aug 4, 2009·Journal of Veterinary Pharmacology and Therapeutics·A Goudah
Apr 20, 2010·Drug Safety : an International Journal of Medical Toxicology and Drug Experience·Hans H Liu
Jun 16, 2010·Drug Development and Industrial Pharmacy·Li-Fang YinQiang Zhang
Jul 14, 2010·Antimicrobial Agents and Chemotherapy·Michelle NelsonAndrew J H Simpson
Nov 6, 2010·Veterinary Medicine International·Ayman Goudah, Sherifa Hasabelnaby
Jun 23, 2012·Veterinary Microbiology·Nathan M BeachLouise Temple
Nov 6, 2012·Veterinary Ophthalmology·Amanda ShermanElizabeth Lutz
Dec 22, 2012·The Journal of Veterinary Medical Science·Ikuo InoueTsuneo Fukata
Feb 26, 2013·Veterinary Microbiology·A Van den EedeK Hermans

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