Levosimendan for ischemic preconditioning in thoracic aortic aneurysm repair

Journal of Cardiac Surgery
Ozgur ErsoyS Fehmi Katircioglu

Abstract

Postoperative neurologic deficit is the most devastating complication after surgical thoracic aorta repair. Cerebrospinal fluid drainage and some medications are used for spinal cord protection during and after the operation. A 25-year-old patient applied to our clinic with a traumatic descending aortic aneurysm. We performed a surgical repair for the aneurysm but could not achieve to place a lumbar catheter to provide cerebrospinal fluid drainage. Levosimendan was chosen for spinal cord ischemic preconditioning because of its vasodilatory effects. Postoperative course was uneventful. Hemodynamic and neurologic complication was not observed, and the patient was discharged from the hospital in the postoperative 5th day. Levosimendan can be used for preconditioning and spinal cord protection from ischemic injury during descending aorta repair. We clearly benefit from the vasodilator peculiarity of the drug for improving spinal cord perfusion.

References

Sep 11, 1992·American Journal of Surgery·L H HollierF J Kazmier
Nov 1, 1984·The Annals of Thoracic Surgery·J C LaschingerF C Spencer
Jun 1, 1995·Journal of Vascular Surgery·G JohanssonJ Swedenborg
Jun 1, 1997·The Annals of Thoracic Surgery·T JuvonenR B Griepp
Nov 21, 2002·The Annals of Thoracic Surgery·Christopher C KwonMark A Malangoni
Mar 2, 2006·Anesthesiology·Wolfgang G Toller, Christian Stranz
Apr 6, 2006·British Journal of Anaesthesia·L TritapepeP Pietropaoli

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Citations

Jun 5, 2012·Journal of Cardiothoracic and Vascular Anesthesia·Wolfgang TollerGiovanni Landoni
Jun 9, 2009·Current Opinion in Anaesthesiology·Markku Salmenperä, Heidi Eriksson

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