Dec 12, 2013

libRoadRunner: A High Performance SBML Compliant Simulator

BioRxiv : the Preprint Server for Biology
Herbert M SauroAndy Somogyi


Summary We describe libRoadRunner, a cross-platform, open-source, high performance C++ library for running and analyzing SBML-compliant models. libRoadRunner was created primarily to achieve high performance, ease of use, portability and an extensible architecture. libRoadRunner includes a comprehensive API, Plugin support, Python scripting and additional functionality such as stoichio-metric and metabolic control analysis. Accessibility and Implementation To maximize collaboration, we made libRoadRunner open source and released it under the Apache License, Version 2.0. To facilitate reuse, we have developed comprehensive Python bindings using SWIG ( and a C API. Li-bRoadRunner uses a number of statically linked third party libraries including: LLVM [[4][1]], libSBML [[1][2]], CVODE, NLEQ2, LAPACK and Poco. LibRoadRunner is supported on Windows, Mac OS X and Linux. Supplementary information Online documentation, build instructions and git source repository are available at <> [1]: #ref-4 [2]: #ref-1

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Mentioned in this Paper

Cross Validation
cDNA Library
Metabolic Control
Active ingredient
Peptide Library

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