PMID: 6980233May 1, 1982Paper

Lichen planus in two immunodeficient hosts

Journal of the American Academy of Dermatology
H S FlamenbaumS Pahwa

Abstract

The exact pathogenic mechanism involved in lichen planus (LP) remains obscure. Two patients who have severe immunodeficiency diseases and who developed LP during the course of their illness are reported here. Both patients had hypogammaglobulinemia and disturbed immune function prior to the development of LP. Although such an association could be coincidental, the development of LP may be related to the underlying immune disturbances. Association of LP with several other disorders of the immune system has been previously observed. Other evidence for the possible involvement of an immunopathogenic mechanism in LP includes (1) deposition of immunoglobulin within the colloid bodies and at the dermoepidermal junction, (2) predominantly T cell dermal infiltrate in LP lesions, and (3) existence of clinical and histologic similarities between graft-versus-host disease and LP.

References

Feb 1, 1978·Archives of Dermatology·I K AronsonA L Lorincz
Aug 1, 1961·Archives of Dermatology·J ALTMAN, H O PERRY
Nov 1, 1950·The British Journal of Dermatology and Syphilis·F F HELLIER

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Citations

Feb 15, 2001·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·I Rodríguez-NúñezJ G Rey
Jun 17, 2015·The Journal of Dermatology·Sei-Ichiro MotegiOsamu Ishikawa
Mar 1, 1997·Oral Surgery, Oral Medicine, Oral Pathology, Oral Radiology, and Endodontics·S R PorterW Barrett
Mar 6, 1998·Critical Reviews in Oral Biology and Medicine : an Official Publication of the American Association of Oral Biologists·C ScullyD Wray
Apr 1, 1986·The British Journal of Dermatology·F C PowellS B Moore
May 1, 1984·Clinical and Experimental Dermatology·G MauduitJ Thivolet
Nov 1, 1988·International Journal of Dermatology·R J Pardo, F A Kerdel

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