Lidocaine pharmacokinetics after cardiac arrest and external cardiopulmonary resuscitation

The American Journal of Cardiology
J Hendrie, C J O'Callaghan

Abstract

Although prolonged cardiopulmonary resuscitation may impair drug metabolism, plasma lidocaine concentrations tended to remain within the therapeutic range after cardiopulmonary resuscitation lasting up to 30 minutes. Thus, the effects of cardiopulmonary resuscitation on lidocaine metabolism appear to be of little importance in the usual clinical situation.

Citations

Aug 25, 2016·The New England Journal of Medicine·Peter J KudenchukUNKNOWN Resuscitation Outcomes Consortium Investigators
Jan 27, 2010·Psychosomatic Medicine·Michael V StantonSherman A James
Dec 19, 2019·Brain : a Journal of Neurology·Edward H Reynolds
Aug 25, 2016·The New England Journal of Medicine·Jayshil J Patel

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