PMID: 7546382DOI: 10.1016/0952-7915(95)80007-7Apr 1, 1995Paper
Life and death during lymphocyte development and function: evidence for two distinct killing mechanisms
Current Opinion in Immunology
A Strasser
Abstract
During their development and after their functional activation most lymphocytes die, either because they fail to receive a survival signal or because they are actively killed. Recent experiments on Bcl-2 and Fas/Apo-1 have provided evidence that these two death processes are subject to distinct genetic control.
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