Life-course socioeconomic disadvantage and lung function: a multicohort study of 70 496 individuals.

The European Respiratory Journal
Vânia Rochamembers of the LIFEPATH Consortium (in alphabetical order):

Abstract

Lung function is an important predictor of health and a marker of physical functioning at older ages. This study aimed to quantify the years of lung function lost according to disadvantaged socioeconomic conditions across the life-course. This multicohort study used harmonised individual-level data from six European cohorts with information on life-course socioeconomic disadvantage and lung function assessed by forced expiratory volume in 1 s (FEV1) and forced vital capacity (FVC). 70 496 participants (51% female) aged 18-93 years were included. Socioeconomic disadvantage was measured in early life (low paternal occupational position), early adulthood (low educational level) and adulthood (low occupational position). Risk factors for poor lung function (e.g. smoking, obesity, sedentary behaviour, cardiovascular and respiratory diseases) were included as potential mediators. The years of lung function lost due to socioeconomic disadvantage were computed at each life stage. Socioeconomic disadvantage during the life-course was associated with a lower FEV1. By the age of 45 years, individuals experiencing disadvantaged socioeconomic conditions had lost 4-5 years of healthy lung function versus their more advantaged counterparts (l...Continue Reading

References

Dec 4, 2003·Journal of Epidemiology and Community Health·C A Mustard, J Etches
Apr 15, 2004·International Journal of Epidemiology·Benita JacksonUNKNOWN CARDIA Study
May 15, 2004·Journal of Epidemiology and Community Health·M HuismanJ P Mackenbach
Jul 17, 2004·International Journal of Epidemiology·Archana Singh-ManouxMichael Marmot
Aug 6, 2004·The European Respiratory Journal·S ShohaimiK T Khaw
Mar 10, 2005·European Journal of Public Health·Mikko LaaksonenEero Lahelma
Aug 2, 2005·The European Respiratory Journal·M R MillerUNKNOWN ATS/ERS Task Force
Sep 2, 2005·The European Respiratory Journal·P K MyintK-T Khaw
Dec 20, 2005·Journal of Epidemiology and Community Health·Bruna GalobardesGeorge Davey Smith
Oct 2, 2007·Lancet·Michael Marmot, UNKNOWN Commission on Social Determinants of Health
Jun 23, 2009·The European Respiratory Journal·C TabakH A Smit
Feb 13, 2010·The European Respiratory Journal·A JohannessenA Gulsvik
Mar 25, 2010·JAMA : the Journal of the American Medical Association·Silvia StringhiniArchana Singh-Manoux
Nov 19, 2011·Annals of the New York Academy of Sciences·Rosemary HiscockMarcus Munafò
Dec 6, 2011·American Journal of Epidemiology·Mel BartleyAmanda Sacker
Jul 25, 2013·BMJ : British Medical Journal·Fanny ArtaudAlexis Elbaz
Jan 5, 2014·American Journal of Respiratory and Critical Care Medicine·Paul W JonesJadwiga A Wedzicha
Aug 16, 2014·Lancet·Dirkje S PostmaMaarten van den Berge
Sep 2, 2014·The Journal of Allergy and Clinical Immunology·Juliana PugmireStefano Guerra
Oct 7, 2014·Journal of the American Geriatrics Society·Séverine SabiaArchana Singh-Manoux
May 8, 2015·Global Health Action·Susan P Phillips, Katarina Hamberg
Sep 19, 2015·Current Environmental Health Reports·Anjum HajatMarie S O'Neill
Nov 24, 2016·International Journal of Epidemiology·Yoav Ben-ShlomoDiana Kuh
Jan 7, 2017·BMC Public Health·Jaime PinillaRosa M Urbanos-Garrido
Jun 18, 2017·F1000Research·Erik Melén, Stefano Guerra
Nov 19, 2017·The Lancet. Respiratory Medicine·Alvar AgustíRosa Faner
Mar 25, 2018·BMJ : British Medical Journal·Silvia StringhiniUNKNOWN LIFEPATH Consortium
Feb 16, 2019·The Lancet. Respiratory Medicine·Alvar Agusti, Rosa Faner
Jun 19, 2019·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Boris ChevalStéphane Cullati
Dec 12, 2019·Journal of Epidemiology and Community Health·Vânia RochaSílvia Fraga

❮ Previous
Next ❯

Citations

Mar 20, 2021·The European Respiratory Journal·Sanja Stanojevic

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.