Life, death and autophagy

Nature Cell Biology
Johnna Doherty, Eric H Baehrecke

Abstract

Autophagy influences cell survival through maintenance of cell bioenergetics and clearance of protein aggregates and damaged organelles. Several lines of evidence indicate that autophagy is a multifaceted regulator of cell death, but controversy exists over whether autophagy alone can drive cell death under physiologically relevant circumstances. Here, we review the role of autophagy in cell death and examine how autophagy interfaces with other forms of cell death including apoptosis and necrosis.

References

Jun 1, 1973·Teratology·J U Schweichel, H J Merker
Jan 1, 1966·Annual Review of Physiology·C De Duve, R Wattiaux
Oct 6, 1998·Nature·N MizushimaY Ohsumi
Oct 20, 1999·The Journal of Cell Biology·T KirisakoY Ohsumi
Dec 2, 2000·Nature·Y IchimuraY Ohsumi
Mar 27, 2001·Nature Reviews. Molecular Cell Biology·Y Ohsumi
Sep 26, 2002·Developmental Biology·Cheng-Yu LeeEric H Baehrecke
Feb 5, 2003·Experimental Cell Research·Sergey Ya ProskuryakovVladimir L Gabai
Feb 21, 2003·Current Biology : CB·Cheng-Yu LeeEric H Baehrecke
Feb 21, 2003·Current Biology : CB·Sharon M GorskiMarco A Marra
Dec 12, 2003·Development·Damali N Martin, Eric H Baehrecke
Nov 6, 2004·Science·Ichiro NakagawaTamotsu Yoshimori
Nov 24, 2004·Nature Cell Biology·Shigeomi ShimizuYoshihide Tsujimoto
Jan 20, 2005·Molecular and Cellular Biology·Patricia BoyaGuido Kroemer
Jun 30, 2005·Journal of Cell Science·Rosa-Ana González-PoloGuido Kroemer
Mar 21, 2006·Proceedings of the National Academy of Sciences of the United States of America·Li YuMichael Lenardo
Sep 26, 2006·Nature Cell Biology·Shida YousefiHans-Uwe Simon
Jan 27, 2007·Cell Death and Differentiation·D N MartinE H Baehrecke
Jan 12, 2008·Autophagy·Brian C MillerHerbert W Virgin
Sep 18, 2008·Journal of Cell Science·Evelyne BergeretMarie-Odile Fauvarque
Sep 27, 2008·Current Biology : CB·Sudeshna Dutta, Eric H Baehrecke
Oct 14, 2008·Autophagy·Francesca ScarlattiPatrice Codogno
Oct 31, 2008·Nature Reviews. Molecular Cell Biology·Guido Kroemer, Beth Levine
Jan 6, 2009·Immunological Reviews·Miguel A SanjuanDouglas R Green

❮ Previous
Next ❯

Citations

Nov 14, 2018·American Journal of Respiratory Cell and Molecular Biology·Santosh K YadavRaymond B Penn
May 17, 2019·Cancer Biology & Therapy·Ruishuang MaHulun Li
Jul 30, 2019·Molecular Reproduction and Development·Camila Ferreira SalesElizete Rizzo
Jul 26, 2019·Journal of Hematology & Oncology·Ji WangJichun Zhou
Aug 10, 2019·Molecular Plant Pathology·Nirbhay Kumar KushwahaDaniel Hofius
Aug 15, 2019·Journal of Materials Chemistry. B, Materials for Biology and Medicine·Christian SecaCiro Isidoro
Jul 31, 2019·Journal of Oral Pathology & Medicine : Official Publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology·Tsai-Yi TsengYi-Hsien Hsieh
Nov 2, 2019·Cancer Medicine·Zu-Cheng XieGang Chen
Dec 28, 2019·DNA and Cell Biology·Xiang-Na Guo, Xin Ma
Aug 24, 2019·Philosophical Transactions of the Royal Society of London. Series B, Biological Sciences·Gianluca Tettamanti, Morena Casartelli
Apr 2, 2020·International Journal of Molecular Sciences·Jicheng Yue, José M López
Nov 22, 2019·Journal of Biological Inorganic Chemistry : JBIC : a Publication of the Society of Biological Inorganic Chemistry·Carla Garza-LombóRodrigo Franco
Sep 6, 2020·Apoptosis : an International Journal on Programmed Cell Death·Chaoyi WuShuyan Wu
Sep 9, 2020·Journal of Molecular Medicine : Official Organ of the Gesellschaft Deutscher Naturforscher Und Ärzte·Li LiuHai Zhang
Jan 30, 2019·Frontiers in Neuroscience·Yulin SunGuozheng Ying
Feb 2, 2019·Nature Structural & Molecular Biology·Masashi Narita
Mar 26, 2019·American Journal of Respiratory Cell and Molecular Biology·Yusi ChengJie Chao
May 14, 2019·International Journal of Cancer. Journal International Du Cancer·Shuangshuang YinHaiyang Yu
Mar 8, 2020·BMC Complementary Medicine and Therapies·Neena Gopinathan PanickerFarah Mustafa
Feb 15, 2020·Journal of Orthopaedic Surgery and Research·Zhengming YangHuimin Tao
May 14, 2020·Nutrients·Assylzhan YessenkyzyTalgat Nurgozhin
Aug 20, 2020·Nature Communications·Tadashi YamamuroTamotsu Yoshimori
Dec 5, 2018·Signal Transduction and Targeted Therapy·Yuhui WuWeidong Han
Apr 20, 2019·International Journal of Molecular Sciences·Salinee JantrapiromMasamitsu Yamaguchi
Feb 8, 2019·Cell Death and Differentiation·Maria Chiara Maiuri, Guido Kroemer
Mar 8, 2019·The Biochemical Journal·Phillip T Newton
Apr 25, 2020·Evidence-based Complementary and Alternative Medicine : ECAM·Luis M Guamán-OrtizNatalia Bailon-Moscoso
Dec 6, 2019·Tissue Engineering. Part B, Reviews·Qinghao ZhangChangsheng Liu
Oct 17, 2019·International Journal of Molecular Sciences·Xiaohong LiAnlong Xu

❮ Previous
Next ❯

Methods Mentioned

BETA
lipidation

Related Concepts

Related Feeds

Apoptosis

Apoptosis is a specific process that leads to programmed cell death through the activation of an evolutionary conserved intracellular pathway leading to pathognomic cellular changes distinct from cellular necrosis

ATG proteins

The discovery of autophagy-related ('ATG') proteins in the 1990s greatly advanced the mechanistic understanding of autophagy and clarified the fact that autophagy serves important roles in various biological processes.

Apoptotic Caspases

Apoptotic caspases belong to the protease enzyme family and are known to play an essential role in inflammation and programmed cell death. Here is the latest research.

Autophagy & Model Organisms

Autophagy is a cellular process that allows degradation by the lysosome of cytoplasmic components such as proteins or organelles. Here is the latest research on autophagy & model organisms

Related Papers

Kangogaku zasshi
Y Noda
Gastroenterology
W F Mommaerts
© 2022 Meta ULC. All rights reserved