Life-history consequences for Daphnia pulex exposed to pharmaceutical carbamazepine

Environmental Toxicology
M LürlingI Roessink

Abstract

The effects of the antiepileptic, analgesic drug carbamazepine on the growth, morphology, and life-history characteristics of Daphnia pulex were examined at nominal concentrations of 0, 0.1, 1, 10, 100, and 200 microg L(-1). At 1 microg carbamazepine L(-1), Daphnia matured and reproduced slightly earlier than did controls, and at a given body length females produced more offspring than did controls or those receiving other treatments. In combination with a relatively high juvenile somatic growth rate and highest total number of progeny produced per female, carbamazepine at 1 microg L(-1) seemed to exert a stimulatory effect. The rates of population growth of the 100 and 200 microg L(-1) treatment groups was 9% and 32% lower, respectively, than the rates of growth of the controls and the Daphnia receiving treatments of up to 10 microg carbamazepine L(-1). At the highest dose, retardation of juvenile somatic growth resulted in delayed maturity and consequently in a lower rate of population growth. Adult somatic growth, spine length, reproductive output, and size of newborns were similar among treatments. Male offspring were only produced in the third broods, with broods that were 8% and 28% male at 1 and 10 microg L(-1), respecti...Continue Reading

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Citations

May 27, 2016·Environmental Science and Pollution Research International·A L OropesaP Palma
Sep 14, 2013·Comparative Biochemistry and Physiology. Toxicology & Pharmacology : CBP·Jae-Sung RheeJae-Seong Lee
Dec 12, 2012·Archives of Environmental Contamination and Toxicology·Kiran LamichhaneThomas W La Point
Nov 5, 2017·Environmental Science and Pollution Research International·Ana Lourdes OropesaPatrícia Palma
Feb 23, 2019·Journal of Environmental Science and Health. Part A, Toxic/hazardous Substances & Environmental Engineering·Katharina HeyeJörg Oehlmann
Jan 13, 2019·Environmental Science and Pollution Research International·Josué Daniel García-Espinoza, Petia Mijaylova Nacheva
Jul 16, 2020·Environmental Science and Pollution Research International·Eva MolnarZsolt Pirger
Jun 2, 2017·Environmental Science and Pollution Research International·Gabrielle MagniezMarc Bonnard
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Aug 21, 2020·Ecotoxicology and Environmental Safety·Matthew NkoomHuike Dong
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