Life-shortening Wolbachia infection reduces population growth of Aedes aegypti

Acta Tropica
Eunho SuhStephen L Dobson

Abstract

Wolbachia bacteria are being introduced into natural populations of vector mosquitoes, with the goal of reducing the transmission of human diseases such as Zika and dengue fever. The successful establishment of Wolbachia infection is largely dependent on the effects of Wolbachia infection to host fitness, but the effects of Wolbachia infection on the individual life-history traits of immature mosquitoes can vary. Here, the effects of life-shortening Wolbachia (wMelPop) on population growth of infected individuals were evaluated by measuring larval survival, developmental time and adult size of Aedes aegypti in intra- (infected or uninfected only) and inter-group (mixed with infected and uninfected) larval competition assays. At low larval density conditions, the population growth of wMelPop infected and uninfected individuals was similar. At high larval densities, wMelPop infected individuals had a significantly reduced population growth rate relative to uninfected individuals, regardless of competition type. We discuss the results in relation to the invasion of the wMelPop Wolbachia infection into naturally uninfected populations.

References

Oct 6, 1997·Proceedings of the National Academy of Sciences of the United States of America·K T Min, S Benzer
Mar 4, 2008·FEMS Microbiology Letters·Kirsten HilgenboeckerJohn H Werren
Sep 17, 2008·Nature Reviews. Microbiology·John H WerrenMichael E Clark
Oct 7, 2008·Applied and Environmental Microbiology·Conor J McMenimanScott L O'Neill
Nov 1, 2008·Science·Lauren M HedgesKaryn N Johnson
Jun 6, 2009·Journal of Medical Entomology·Laurent GavotteStephen L Dobson
Aug 19, 2009·Evolution; International Journal of Organic Evolution·Michael Turelli
Sep 16, 2009·PLoS Neglected Tropical Diseases·Andrew P TurleyElizabeth A McGraw
Oct 13, 2009·Applied and Environmental Microbiology·Eunho SuhStephen L Dobson
Sep 3, 2010·Journal of Invertebrate Pathology·Laurent GavotteStephen L Dobson
Oct 12, 2010·Parasites & Vectors·Constantianus Jm KoenraadtLaura C Harrington
May 5, 2011·PLoS Neglected Tropical Diseases·Penelope A HancockH Charles J Godfray
May 7, 2011·EMBO Reports·Iñaki Iturbe-OrmaetxeScott L O' Neill
Oct 7, 2011·BMC Evolutionary Biology·Philip R CrainStephen L Dobson
Nov 30, 2011·Proceedings of the National Academy of Sciences of the United States of America·Marcus S C BlagroveSteven P Sinkins
Nov 8, 2012·PLoS Neglected Tropical Diseases·Andrew F van den HurkScott L O'Neill
Feb 16, 2013·Nature Reviews. Microbiology·Elizabeth A McGraw, Scott L O'Neill
Apr 12, 2013·Proceedings. Biological Sciences·Ary A Hoffmann, Michael Turelli
Aug 21, 2013·PLoS Neglected Tropical Diseases·Yixin H YeElizabeth A McGraw
Nov 21, 2013·Acta Tropica·Kostas BourtzisJeremie R L Gilles
Mar 4, 2014·PLoS Neglected Tropical Diseases·Francesca D FrentiuScott L O'Neill
Apr 16, 2014·The American Journal of Tropical Medicine and Hygiene·Perran A RossAry A Hoffmann
Aug 27, 2014·Ecological Applications : a Publication of the Ecological Society of America·Gordana RasićAry A Hoffmann
Sep 12, 2014·PLoS Neglected Tropical Diseases·Ary A HoffmannScott L O'Neill
Mar 20, 2015·Science Translational Medicine·Neil M FergusonCameron P Simmons
Jun 27, 2015·PLoS Neglected Tropical Diseases·Yixin H YeElizabeth A McGraw
Jul 24, 2015·PLoS Neglected Tropical Diseases·Scott A RitchieAry A Hoffmann
Jan 9, 2016·PLoS Neglected Tropical Diseases·Perran A RossAry A Hoffmann
May 9, 2016·Cell Host & Microbe·Heverton Leandro Carneiro DutraLuciano Andrade Moreira

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Citations

Nov 22, 2019·FEMS Microbiology Letters·Sergio López-Madrigal, Elves H Duarte
Oct 16, 2019·Journal of Insect Science·Gemma M McLaughlin, Peter K Dearden
Jun 26, 2020·Frontiers in Microbiology·Mariana MateosGeorge Tsiamis

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