Life-threatening hyponatremia due to the syndrome of inappropriate secretion of antidiuretic hormone (SIADH) in a patient with the miller fisher syndrome.

Endocrine Practice : Official Journal of the American College of Endocrinology and the American Association of Clinical Endocrinologists
S T Ramaprasad, L Poretsky

Abstract

We report a life-threatening hyponatremia due to SIADH which developed suddenly in a patient with the Miller Fisher syndrome (a variant of Guillian Barré syndrome characterized by complete ophthalmoplegia, ataxia, and areflexia). A 55 year-old female was admitted with a clinical picture of the Miller Fisher syndrome. Cerebrospinal fluid was acellular with elevated proteins, and electromyographic changes were characteristic of polyneuropathy. On the third day of admission the patient was found to be mentally confused with a serum sodium of 108 mmol/L. Serum osmolality was 236 mosm/L and urine osmolality was 636 mosm/L. Urine sodium was 103 mmol/L. The serum sodium normalized after treatment with a single dose of intravenous furosemide, hypertonic saline infusion and fluid restriction. To our knowledge, this is the first description of SIADH developing in a patient with the Miller Fisher syndrome.

References

Jun 1, 1971·The American Journal of Medicine·P Lichtenfeld
Oct 1, 1971·Postgraduate Medical Journal·A G Davies
May 1, 1967·The American Journal of Medicine·F C Bartter, W B Schwartz
Mar 1, 1982·Annals of Neurology·M S HochmanJ V Handwerker
Mar 1, 1993·Critical Care Medicine·E F HundG M McKhann
Jul 1, 1965·Archives of Internal Medicine·W C COOPERS P WANG

❮ Previous
Next ❯

Citations

Mar 3, 2009·Journal of Neurology·Raffaele IorioGabriella Silvestri
Dec 3, 2009·Journal of Neuro-ophthalmology : the Official Journal of the North American Neuro-Ophthalmology Society·Lee A SnyderNeil R Miller
Jan 13, 2000·Progress in Neuro-psychopharmacology & Biological Psychiatry·R D Oades, R Daniels
Jun 16, 2011·Acta Paediatrica·Hassib ChehadeFrancois Cachat

❮ Previous
Next ❯

Related Feeds

Ataxias

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on different types of ataxias here.

Ataxias (MDS)

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

Ataxia

Ataxia is a neurological condition characterized by lack of voluntary coordination of muscle movements including loss of coordination, balance, and speech. Discover the latest research on ataxia here.

CSF & Lymphatic System

This feed focuses on Cerebral Spinal Fluid (CSF) and the lymphatic system. Discover the latest papers using imaging techniques to track CSF outflow into the lymphatic system in animal models.

Related Papers

Ophthalmologica. Journal international d'ophtalmologie. International journal of ophthalmology. Zeitschrift für Augenheilkunde
Y IgarashiK Ogasawara
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine
Hiroshi KitamuraHiide Yoshino
International Journal of Pediatric Endocrinology
Yoon Hi ChoGeoffrey Ambler
Neurologia Medico-chirurgica
M MatsumaeF Tsubai
© 2022 Meta ULC. All rights reserved