Life with nucleosomes: chromatin remodelling in gene regulation

Current Opinion in Cell Biology
P D Gregory, W Hörz

Abstract

In the past year, the role of chromatin has emerged at the forefront of transcription research. Discovery and characterisation of the chromatin modifying machinery have significantly advanced our understanding of the molecular activities that establish a transcriptionally competent substrate in vivo, and have underscored the importance of the part played by chromatin in the regulation of transcription.

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