Lifecycles of EBV and cancer

Uirusu
Takayuki Murata

Abstract

Epstein-Barr virus (EBV) is a member of gamma-herpesvirus, which can cause various types of tumor. Coexisting with the host for a long period of time, it has evolved unique and sophisticated strategy for survival by taking complicated, tactical modes of infection. Such modes include latent and lytic infections, and latent state is further categorized into four types. Differences and transitions in such lifestyles are significantly associated not only with virus amplification, but also with pathology and advancement of the disorders. I here review oncogenesis and pathogenesis of EBV-related disorders, especially focusing on our recent results on the modes of EBV infection.

References

Jun 15, 1991·Proceedings of the National Academy of Sciences of the United States of America·G GaidanoR Dalla-Favera
Nov 27, 2002·Seminars in Cancer Biology·Kwok-Wai Lo, Dolly P Huang
Jan 9, 2003·The Lancet Oncology·Antonino Carbone
Sep 24, 2004·Reviews in Medical Virology·Tatsuya TsurumiAyumi Kudoh
Apr 9, 2005·British Journal of Haematology·Hilary WilliamsDorothy H Crawford
Oct 11, 2005·Hematological Oncology·Daniela CapelloGianluca Gaidano
Dec 31, 2005·International Journal of Cancer. Journal International Du Cancer·Andreas BräuningerRalf Küppers
Dec 19, 2007·PLoS Pathogens·Xianming YuJanet E Mertz
Feb 10, 2009·The Journal of Immunology : Official Journal of the American Association of Immunologists·Daniëlle HorstMaaike E Ressing
Apr 22, 2009·The Journal of Experimental Medicine·Roland SchmitzRalf Küppers
Jul 22, 2009·Seminars in Cancer Biology·Martin RoweAlan B Rickinson
Jan 19, 2010·Proceedings of the National Academy of Sciences of the United States of America·Markus KallaWolfgang Hammerschmidt
Jun 4, 2010·Pathology International·Masashi Fukayama
Apr 29, 2011·The Journal of Biological Chemistry·Takayuki MurataTatsuya Tsurumi
Jul 5, 2012·Cancer Research·Atsushi KanedaMasashi Fukayama
Nov 20, 2012·Proceedings of the National Academy of Sciences of the United States of America·Chi Man TsangSai Wah Tsao
Jan 15, 2013·The Journal of Immunology : Official Journal of the American Association of Immunologists·Bryan D GriffinEmmanuel Wiertz
Dec 18, 2013·Reviews in Medical Virology·Takayuki Murata, Tatsuya Tsurumi
Mar 1, 2014·Reviews in Medical Virology·Takayuki MurataHiroshi Kimura

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