Lifelong risk factors for osteoporosis and fractures in elderly women with low body mass index--a population-based study

Bone
R KorpelainenS Keinänen-Kiukaanniemi

Abstract

Low body weight is associated with an increased risk for osteoporosis and fractures, but the contribution of other lifestyle related factors have not been previously studied within lean elderly women. The present study evaluated the association between lifelong lifestyle factors and bone density, falls and postmenopausal fractures in elderly women with low body mass index (BMI). A population-based sample of 1,222 women aged 70 to 73 years was stratified by BMI tertiles, and all 407 women in the lowest tertile participated. Data on falls and postmenopausal fractures, physical activity, functional capacity, calcium intake, smoking, alcohol intake and medical factors at different ages were obtained by a questionnaire. Calcaneum bone mass as broadband ultrasound attenuation (BUA) was assessed with a quantitative ultrasound (QUS) device, and bone mineral density (BMD) at the distal radius was measured with a dual-energy X-ray absorptiometry (DXA). Low current physical activity was associated with lower calcaneum BUA and factors associated with higher BUA were body weight, low lifetime occupational physical activity, hormone replacement and type 2 diabetes. Weight, type 2 diabetes and thiatzide use were associated with higher radius ...Continue Reading

References

Mar 1, 1991·Age and Ageing·S IliffeS Gallivan
Oct 1, 1987·Acta diabetologica latina·G IsaiaG M Molinatti
Mar 23, 1995·The New England Journal of Medicine·S R CummingsT M Vogt
Jul 1, 1995·Annals of Epidemiology·S B JaglalG A Darlington
Sep 4, 1997·The New England Journal of Medicine·B Dawson-HughesG E Dallal
Mar 14, 1998·Calcified Tissue International·M WeissE Dolev
May 16, 1998·American Journal of Epidemiology·H BurgerH A Pols
May 29, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·A A IsmailA J Silman
Nov 9, 2000·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·H LuukinenS L Kivelä
Feb 24, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·P Dargent-MolinaUNKNOWN EPIDOS Group
Oct 3, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·D J van der VoortG J Dinant
Oct 3, 2001·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M LuntJ Reeve
May 23, 2002·The Annals of Pharmacotherapy·Rahamim AvisarDov Weinberger
May 6, 2003·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·Cathleen S Colón-EmericKenneth W Lyles
Oct 23, 2003·The Journals of Gerontology. Series A, Biological Sciences and Medical Sciences·Kimberly A FaulknerMichael C Nevitt
Dec 23, 2003·Journal of the American Geriatrics Society·Kristine E EnsrudUNKNOWN Study of Osteoporotic Fractures Research Group
Jul 1, 2004·Preventive Medicine·Tommi SulanderAntti Uutela

❮ Previous
Next ❯

Citations

Nov 1, 2007·Der Radiologe·C Kasperk
Sep 4, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·B MezukS H Golden
Oct 27, 2007·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·N YoshimuraT Nakamura
Feb 1, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·M KärkkäinenE Alhava
Dec 25, 2008·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·S L BrennanA E Wluka
Sep 24, 2009·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·J ØyenG Haugeberg
May 19, 2010·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·E GuilleyT Chevalley
Dec 12, 2012·Archives of Osteoporosis·Alice M J TorpyJulie A Pasco
May 11, 2010·Hormone and Metabolic Research = Hormon- Und Stoffwechselforschung = Hormones Et Métabolisme·G CizzaG Csako
Nov 1, 2006·Proceedings of the National Academy of Sciences of the United States of America·Raz YirmiyaItai Bab
Jul 5, 2008·Journal of Bone and Mineral Metabolism·Adriana PérezNori Tolosa de Talamoni
Dec 19, 2009·Medicine and Science in Sports and Exercise·Henri IsojärviRaija Korpelainen
Dec 20, 2012·Wiener klinische Wochenschrift·Karin Schindler, Bernhard Ludvik
Dec 1, 2008·Clinical Reviews in Bone and Mineral Metabolism·Briana Mezuk
Nov 18, 2008·Gynecological Endocrinology : the Official Journal of the International Society of Gynecological Endocrinology·Shaohai WangZehua Wang
Apr 9, 2009·Expert Opinion on Pharmacotherapy·M S van BrusselW F Lems
Sep 11, 2008·Climacteric : the Journal of the International Menopause Society·A CagnacciA Volpe
Sep 15, 2009·Trends in Endocrinology and Metabolism : TEM·Giovanni CizzaGyorgy Csako
Apr 8, 2016·Wiener klinische Wochenschrift·Karin SchindlerBernhard Ludvik
Feb 6, 2013·Progress in Neuro-psychopharmacology & Biological Psychiatry·P MalikB Sperner-Unterweger
Oct 26, 2014·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·C M OliveiraM F Pina
Mar 13, 2014·Archives of Osteoporosis·Sara LourençoHenrique Barros
Dec 17, 2008·Clinical Orthopaedics and Related Research·Andrew J SynnCharles S Day
Jul 5, 2016·Neurologia i neurochirurgia polska·Katarzyna KępczyńskaBeata Zakrzewska-Pniewska
Apr 14, 2019·Wiener klinische Wochenschrift·Karin SchindlerBernhard Ludvik
Jun 13, 2020·Current Osteoporosis Reports·R ViggersJ Starup-Linde
Jun 26, 2021·Osteoporosis International : a Journal Established As Result of Cooperation Between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA·G ValentinC L Gregson

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