PMID: 573445Jun 12, 1979

Lifelong variations in heart rates in SPF Sprague Dawley rats of both sexes. Statistical correlations with body weights

Pflügers Archiv : European journal of physiology
M Stupfel, D Costagliola

Abstract

In unanesthetized Sprague Dawleys, SPF, of both sexes, housed in DL12:12 (100lux), at a temperature of 18--23 degrees C and a hygrometry of 60--75%, the measurements of heart frequencies during most part of their life point out a continuous decrease with age and an always higher (40--20 c.min-1) heart rate in females than in males. Significant correlations between heart rate and body weight can account for these heart rates variations. Between the ages of 72 and 589 days, which corresponds to the growth period, a linear relationship was established between Log heart rate (y; c. min-1) and Log body weight (x; gram); for males: Log y = 0.122 Log X +Log 938 and for females: Log y = -0.166 Log X + Log 1217. After the age of 600 days, which corresponds to senescence, decreases in heart rate as well as in body weight were observed in both sexes.

References

Sep 4, 1976·Lancet·J M ClarkeG R Venning
Aug 1, 1975·The American Journal of Physiology·S Lahiri
Apr 1, 1975·Journal of Applied Physiology·R D PhillipsN W King
Sep 1, 1975·The American Journal of Physiology·R D BuñagN Mueting
Jul 1, 1973·Journal of Gerontology·D A RothbaumN W Shock
Oct 17, 1973·Pflügers Archiv : European journal of physiology·E Humpeler, H Amor
Dec 1, 1971·The American Journal of Physiology·J E Morhardt, S S Morhardt
Sep 1, 1970·Journal of Comparative and Physiological Psychology·R GoldsteinJ A Stern
Dec 1, 1970·Journal of Applied Physiology·S GlagovR G Page
Apr 1, 1968·Journal of Gerontology·H J MontoyeD A Cunningham
Dec 1, 1966·The Anatomical Record·B B Krames, E J Van Liere
Mar 1, 1967·The American Journal of Physiology·E F Adolph
Sep 30, 1967·Nature·J E Kinnear, G D Brown
Oct 1, 1955·Journal of Gerontology·B N BERG, C R HARMISON
Jul 1, 1960·Journal of Applied Physiology·E L HUNT, D J KIMELDORF
Nov 21, 1927·The Journal of Physiology·A J Clark
Oct 1, 1946·Proceedings of the Society for Experimental Biology and Medicine·L E MOSES

Citations

Mar 1, 1981·Physiology & Behavior·M StupfelH Thierry
Jun 1, 1980·Mechanisms of Ageing and Development·J Weil-FugazzaM Stupfel
Jan 1, 1985·The Science of the Total Environment·V H Demaria PesceC Lemercerre
Sep 1, 1987·The Science of the Total Environment·V H Demaria PesceC Lemercerre
Dec 1, 1995·Journal of Neuroscience Methods·L A Reina, R P Yezierski

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