Lifestyle and pregnancy complications in polycystic ovary syndrome: The SCOPE cohort study

Clinical Endocrinology
Mahnaz Bahri KhomamiC T Roberts

Abstract

To investigate the risk of pregnancy complications in women with and without polycystic ovary syndrome after consideration of lifestyle factors. Prospective cohort. Participants (n = 5628) were apparently healthy nulliparous women with singleton pregnancies from the Screening for Pregnancy Endpoints study in New Zealand, Australia, United Kingdom and Ireland. Multivariable regression models were performed assessing the association of self-reported polycystic ovary syndrome status with pregnancy complications with consideration of lifestyle factors at the 15th week of gestation. Women with polycystic ovary syndrome (n = 354) were older, had a higher socio-economic index and body mass index and were less likely to consume alcohol and smoke but more likely to do vigorous exercise and take multivitamins. In univariable analysis, polycystic ovary syndrome was associated with increased risk of gestational diabetes (OR: 2.2, 95% CI: 1.2, 4.0). In multivariable models, polycystic ovary syndrome was only significantly associated with decreased risk of large for gestational age (OR: 0.62, 95% CI: 0.40, 0.98) with a population attributable risk of 0.22%. None of the other outcomes were attributable to polycystic ovary syndrome status. Pol...Continue Reading

References

Aug 5, 2000·The Australian & New Zealand Journal of Obstetrics & Gynaecology·M A BrownUNKNOWN Austalasian Society of the Study of Hypertension in Pregnancy
Aug 8, 2006·Human Reproduction Update·C M BoomsmaN S Macklon
Sep 12, 2007·CMAJ : Canadian Medical Association Journal = Journal De L'Association Medicale Canadienne·K S JosephAlexander C Allen
Aug 27, 2009·The Open Nursing Journal·Reeta LampinenPäivi Kankkunen
Oct 8, 2009·Current Opinion in Obstetrics & Gynecology·Kathleen M RasmussenAnn L Yaktine
Jan 7, 2010·Journal of Psychosomatic Obstetrics and Gynaecology·Lisa MoranAmanda Deeks
Jan 12, 2010·American Journal of Obstetrics and Gynecology·Allison S BryantA Eugene Washington
Mar 2, 2010·Women's Health·Lisa J MoranHelena J Teede
Nov 17, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·L M E McCowanUNKNOWN SCOPE consortium
Dec 8, 2010·BJOG : an International Journal of Obstetrics and Gynaecology·I StreulingR von Kries
Jul 15, 2011·American Journal of Obstetrics and Gynecology·Lucinda E KjerulffDaniel Duffy
Oct 15, 2011·BMJ : British Medical Journal·Nathalie RoosOlof Stephansson
May 24, 2012·Obstetrics and Gynecology·Carlos A CarrenoUNKNOWN Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) Maternal-Fetal Medicine Units (MFMU)
Jul 7, 2012·Paediatric and Perinatal Epidemiology·Usha RamakrishnanReynaldo Martorell
Sep 12, 2012·BMC Research Notes·Hayfaa A WahabiRasmieh A Alzeidan
Nov 2, 2012·Obesity Reviews : an Official Journal of the International Association for the Study of Obesity·S S LimL J Moran
Feb 2, 2013·Research Quarterly for Exercise and Sport·Danielle Symons DownsSeonAe Yeo
Jun 27, 2013·Reproductive Biology and Endocrinology : RB&E·Jun Z QinHong Y Chen
May 16, 2014·Journal of Human Reproductive Sciences·Sunita R TandulwadkarNirzari T Mangeshikar
May 31, 2014·The Journal of Clinical Endocrinology and Metabolism·Stefano PalombaFulvio Zullo
Jun 11, 2014·Endocrine·Renato Pasquali, Pasquali Renato
Jul 6, 2014·Journal of Obesity·Antonia RestallLesley M E McCowan
Nov 25, 2014·Acta Obstetricia Et Gynecologica Scandinavica·Hanne MummDorte Glintborg
Jun 29, 2015·Human Reproduction Update·Stefano PalombaBart C J M Fauser
Aug 12, 2015·International Journal of Women's Health·Stefano PalombaGiovanni Battista La Sala
Dec 5, 2015·Clinical Medicine : Journal of the Royal College of Physicians of London·Thomas M BarberStephen Franks
Dec 24, 2015·The Journal of Clinical Endocrinology and Metabolism·Flavia TosiPaolo Moghetti
Feb 9, 2016·Seminars in Reproductive Medicine·Anju E JohamRoger Hart
Apr 12, 2016·International Journal of Endocrinology·Qing XiaoFang-Ling Zeng
May 31, 2016·F1000Research·Ariadna Forray

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Citations

Jul 28, 2020·American Journal of Obstetrics and Gynecology·Iris LeeAnuja Dokras

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