Lifestyle factors and disease-specific differences in subgroups of Swedish Myasthenia Gravis

Acta Neurologica Scandinavica
Elisabet WesterbergAnna R Punga

Abstract

To evaluate disease-specific differences between Myasthenia Gravis (MG) subgroups and compare patterns of lifestyle between MG patients and population controls. All MG patients (n = 70) in Jönköping County, Sweden, were invited to answer a disease-specific questionnaire, containing questions about disease-specific data, lifestyle, comorbidity, and mental fatigue. The patients were clinically evaluated. Four hundred age- and gender-matched population controls were invited to answer the nondisease-specific part of the questionnaire. Disease-specific issues were compared between MG subgroups. Lifestyle-related factors and concomitant conditions were compared to the population controls. Forty MG patients and 188 population controls participated in the study. In the late-onset MG (LOMG; N = 18) subgroup, the male predominance was higher than previously reported. In the early-onset MG (EOMG; N = 17) subgroup, time to diagnosis was longer, fatigue was higher, and bulbar weakness was the dominant symptom (65%). Compared to their matched population controls, LOMG patients were more obese (OR = 13.7, P = 0.015), ate less fish (OR = 4.1, P = 0.012), tended to smoke more (OR = 4.1, P = 0.086), and tended to be employed as manual laborers m...Continue Reading

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Citations

Jan 30, 2019·Acta Neurologica Scandinavica·Madhu NagappaArun B Taly
Apr 5, 2019·Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia·Wenling AoYajie Liu
Sep 2, 2020·Brain and Behavior·Elisabet Westerberg, Anna Rostedt Punga
Dec 17, 2020·Neurological Research and Practice·Francesca PasqualinDomenico M Bonifati
May 27, 2021·Neuromuscular Disorders : NMD·Annabel M RuiterMartijn R Tannemaat
Jul 26, 2021·Neuromuscular Disorders : NMD·Linda Kahr AndersenJohn Vissing
Oct 13, 2021·Neuromuscular Disorders : NMD·Nils Erik GilhusJacqueline Palace

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