Lifestyle measures in the management of gastro-oesophageal reflux disease: clinical and pathophysiological considerations

Therapeutic Advances in Chronic Disease
J H-E Kang, J Y Kang

Abstract

Several lifestyle and dietary factors are commonly cited as risk factors for gastro-oesophageal reflux disease (GORD) and modification of these factors has been advocated as first-line measures for the management of GORD. We performed a systematic review of the literature from 2005 to the present relating to the effect of these factors and their modification on GORD symptoms, physiological parameters of reflux as well as endoscopic appearances. Conflicting results existed for the association between smoking, alcohol and various dietary factors in the development of GORD. These equivocal findings are partly due to methodology problems. There is recent good evidence that weight reduction and smoking cessation are beneficial in reducing GORD symptoms. Clinical and physiological studies also suggest that some physical measures as well as modification of meal size and timing can also be beneficial. However, there is limited evidence for the role of avoiding alcohol and certain dietary ingredients including carbonated drinks, caffeine, fat, spicy foods, chocolate and mint.

References

Feb 1, 1977·Digestion·C Stanciu, J R Bennett
Apr 1, 1978·Gut·S E Kaufman, M D Kaye
Oct 1, 1977·Gut·D K ChattopadhyayT T Irvin
Nov 1, 1976·The American Journal of Digestive Diseases·O T NebelD O Castell
Nov 9, 1975·The New England Journal of Medicine·S Cohen, G H Booth
Oct 1, 1990·Alimentary Pharmacology & Therapeutics·S Lanzon-MillerJ R Wood
Mar 15, 1990·Annals of Internal Medicine·B B KrausD O Castell
Jan 1, 1990·Gut·P J Kahrilas, R R Gupta
Jun 23, 1989·JAMA : the Journal of the American Medical Association·C S ClarkD O Castell
Aug 1, 1989·Gut·P DurouxA L Blum
May 1, 1988·Metabolism: Clinical and Experimental·O WisénC Johansson
Oct 1, 1987·Journal of Clinical Gastroenterology·M M BerensonR M McCallum
May 1, 1988·Digestive Diseases and Sciences·J W HamiltonM Reichelderfer
Jun 1, 1987·Gastroenterology·N E SchindlbeckS A Müller-Lissner
Oct 16, 1987·JAMA : the Journal of the American Medical Association·G C VitaleA Cuschieri
Oct 1, 1985·Gastroenterology·R H HollowayR W McCallum
May 1, 1973·The American Journal of Digestive Diseases·J C BabkaD O Castell
Sep 30, 1972·British Medical Journal·C Stanciu, J R Bennett
Jan 1, 1981·Digestion·P R SalmonA E Read
Feb 1, 1980·The Journal of Clinical Investigation·J DentD J Petrie
Jul 17, 1980·The New England Journal of Medicine·S Cohen
Jun 1, 1994·Journal of Clinical Gastroenterology·L C KatzD O Castell
May 1, 1996·Digestive Diseases and Sciences·K IwakiriY Nakagawa
Nov 1, 1996·Scandinavian Journal of Gastroenterology·A KjellinK Thor
Jun 1, 1997·The British Journal of Surgery·M MorinoC Garrone
Jun 1, 1997·Digestive Diseases and Sciences·L GrandeC Pera
Jun 1, 1997·Alimentary Pharmacology & Therapeutics·C PehlH Kaess
Dec 31, 1997·Journal of Clinical Gastroenterology·C PehlH Kaess
Apr 29, 1998·The American Journal of Medicine·D A RevickiS Sorensen
Aug 15, 1998·Digestion·J Dent
Sep 10, 1998·Obesity Surgery·A WestlingS Gustavsson
Mar 2, 1999·Neurogastroenterology and Motility : the Official Journal of the European Gastrointestinal Motility Society·K C KapurS A Riley
Jun 12, 1999·Scandinavian Journal of Gastroenterology·C A Fraser-MoodieG K Holmes
Jun 23, 1999·The American Journal of Medicine·G R LockeL J Melton
Nov 26, 1999·Digestive Diseases and Sciences·B L FisherA G Little
Jan 19, 2000·Obesity Surgery·J B Dixon, P E O'Brien

❮ Previous
Next ❯

Citations

Feb 2, 2017·Current Opinion in Gastroenterology·Sajiv Sethi, Joel E Richter
Dec 20, 2020·Digestive and Liver Disease : Official Journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver·Yuan ChengJunxiang Li
Aug 14, 2021·JGH Open : an Open Access Journal of Gastroenterology and Hepatology·Khean-Lee GohReuben Kong-Min Wong

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.