Lifetime coffee consumption, pineal gland volume, and sleep quality in late life

Sleep
Jeongbin ParkKi Woong Kim

Abstract

Previous studies have shown that coffee consumption may suppress the production of melatonin in pinealocytes through competitive inhibition of adenosine A2 receptors by caffeine. We investigated the impact of lifetime coffee consumption on pineal gland volume and the resulting effects on sleep quality. We enrolled 162 cognitively normal elderly individuals among the participants in the Korean Longitudinal Study on Cognitive Aging and Dementia. We evaluated the patterns and amounts of coffee consumption using a study-specific standardized interview and assessed sleep quality using the Pittsburgh Sleep Quality Index. We measured the volume of pineal parenchyma (VPP) by manually segmenting the pineal gland on high-resolution three-dimensional T1-weighted magnetic resonance images. We examined the impact of lifetime coffee consumption on the VPP and the resulting effects on sleep quality using analysis of covariance, multiple linear regression, and mediation analyses. We found that smaller VPP was associated with higher cumulative lifetime coffee consumption. Participants who consumed more than 60 cup-years of coffee had VPPs that were smaller by about 20% than individuals who consumed less than 60 cup-years of coffee. The VPP medi...Continue Reading

References

Oct 1, 1990·Journal of Neurochemistry·D ReynaudN Sarda
Jan 1, 1987·Acta Neuropathologica·R J Seitz, W Wechsler
Dec 4, 1989·Neuroscience Letters·A GharibH Pacheco
Apr 1, 1989·British Journal of Clinical Pharmacology·J E JamesN R Scott
Nov 1, 1988·Pflügers Archiv : European journal of physiology·J FalcónJ P Collin
Jan 1, 1988·The Journal of International Medical Research·D H Mniszek
Dec 1, 1983·Clinical Genetics·L WetterbergJ Lindsten
Dec 1, 1981·The American Journal of Anatomy·R J Reiter
Apr 1, 1995·The Journal of Clinical Endocrinology and Metabolism·F SchmidtF Waldhauser
Apr 1, 1995·Journal of Pineal Research·J D BergiannakiC N Stefanis
Jul 16, 1994·BMJ : British Medical Journal·I HaimovP Lavie
Mar 1, 1994·Journal of Neurosurgery·J S FainG M Miller
Sep 1, 1995·Journal of Pineal Research·J FalcónJ P Collin
Oct 24, 1998·American Journal of Epidemiology·G E FraserD J Shavlik
Mar 12, 1999·Neuroscience and Biobehavioral Reviews·A Nehlig
Mar 7, 2001·European Journal of Pharmacology·K J ElliottM A Rea
Jul 4, 2001·Nature Reviews. Neuroscience·R M Buijs, A Kalsbeek
Nov 1, 2003·Sleep Medicine·Lotan ShiloLouis Shenkman
Jan 31, 2004·Journal of the International Neuropsychological Society : JINS·Dong Y LeeJong I Woo
Sep 27, 2005·Experimental Gerontology·S R Pandi-PerumalD P Cardinali
Mar 2, 2006·Critical Reviews in Food Science and Nutrition·Jane V Higdon, Balz Frei
May 23, 2006·Radiology·Anne G Osborn, Michael T Preece
Apr 25, 2007·Frontiers in Neuroendocrinology·Oren Froy
Jul 10, 2007·The American Journal of Clinical Nutrition·Marilyn C CornelisHannia Campos
May 12, 2009·Neuroscience and Biobehavioral Reviews·Jennifer L Temple
Jul 25, 2009·Journal of Magnetic Resonance Imaging : JMRI·Ingo NölteChristoph Groden
Aug 12, 2009·International Journal of Developmental Neuroscience : the Official Journal of the International Society for Developmental Neuroscience·Bo SunShuwei Liu
Apr 29, 2010·Dementia and Geriatric Cognitive Disorders·Tae Hui KimKi Woong Kim
Jan 12, 2011·Proceedings of the National Academy of Sciences of the United States of America·Ilia N KaratsoreosBruce S McEwen
Jun 21, 2011·Biochemical and Biophysical Research Communications·Hideaki OikeNorio Ishida
Jun 28, 2011·Journal of Affective Disorders·Samuel SarrazinJosselin Houenou
Feb 21, 2013·Journal of Alzheimer's Disease : JAD·Marie-Noël VercambreJae H Kang
May 22, 2013·PloS One·Eduardo Ferracioli-OdaMichael H Bloch

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Medsurg Nursing : Official Journal of the Academy of Medical-Surgical Nurses
C Smyth
No shinkei geka. Neurological surgery
T MasuzawaN Yamada
© 2022 Meta ULC. All rights reserved