Ligand-Controlled Regiodivergent Copper-Catalyzed Alkylboration of Alkenes

Angewandte Chemie
Wei SuYao Fu

Abstract

A novel copper-catalyzed regiodivergent alkylboration of alkenes with bis(pinacolato)diboron and alkyl halides has been developed. The regioselectivity of the alkylboration was controlled by subtle differences in the ligand structure. The reaction thus enables the practical, regiodivergent synthesis of two different alkyl boronic esters with complex structures from a single alkene.

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Citations

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