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Ligation-anchored PCR unveils immune repertoire of TCR-beta from whole blood

bioRxiv

Jul 11, 2014

Fan Gao, Kai Fa Wang

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Abstract

Background As one of the genetic mechanisms for adaptive immunity, V(D)J recombination generates an enormous repertoire of T-cell receptors (TCRs). With the development of high-throughput sequencing techniques, systematic exploration of V(D)J recombination becomes possible. Multiplex PC...read more

Mentioned in this Paper

Blood Specimen
Polymerase Chain Reaction
Oligonucleotide Primers
Study
Alpha-beta T-Cell Receptor
Malignant Meningioma
DNA Amplification
RNA
CEREBELLAR DEGENERATION-RELATED AUTOANTIGEN 3
Anaplastic Oligodendroglioma
4
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  • Ligation-anchored PCR unveils immune repertoire of TCR-beta from whole blood

    bioRxiv

    Jul 11, 2014

    Fan Gao, Kai Fa Wang

    PMID: 990007062

    DOI: 10.1101/007062

    Abstract

    Background As one of the genetic mechanisms for adaptive immunity, V(D)J recombination generates an enormous repertoire of T-cell receptors (TCRs). With the development of high-throughput sequencing techniques, systematic exploration of V(D)J recombination becomes possible. Multiplex PC...read more

    Mentioned in this Paper

    Blood Specimen
    Polymerase Chain Reaction
    Oligonucleotide Primers
    Study
    Alpha-beta T-Cell Receptor
    4

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