Light and laser therapies for the treatment of sebaceous gland hyperplasia a review of the literature

Journal of the European Academy of Dermatology and Venereology : JEADV
B J SimmonsEuropean Dermatology Forum

Abstract

Sebaceous gland hyperplasia (SGH) is a benign cutaneous condition that presents primarily on the face and increases with UVB exposure and ageing. These lesions are a common cosmetic concern but are difficult to treat, as the entire sebaceous gland needs to be destroyed to prevent recurrence. Traditional methods of treatment include: cryosurgery, electrodessication, curettage, shave excision and topical trichloroacetic acid. These methods have an increased risk of skin discoloration and scarring to the area of treatment that may lead to inferior cosmetic outcomes. Alternatively, oral isotretinoin can treat SGH, but is a known teratogen in pregnancy and has high relapse rates with discontinuation. A systematic review of the literature was performed to look at photodynamic therapy (PDT) and laser treatment for SGH. According to the results of this study, PDT, lasers and combinations of the two treatments were found to offer alternatives to the more conventional techniques with better outcomes. In particular, the use of wavelength-specific laser for the sebaceous gland of 1720 nm were found to have better outcomes and provide minimal damage to surrounding tissues. Additionally, combination PDT with aminolevulinic acid and pre-treat...Continue Reading

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Citations

Dec 29, 2015·Biotechnology Journal·Mohammod Kabir BhuyanThomas Boland
Mar 17, 2017·Journal of Cutaneous Medicine and Surgery·Hatice Ataş, Müzeyyen Gönül
Feb 6, 2020·The Journal of Dermatological Treatment·Lama Hussein, Conal M Perrett
Oct 9, 2019·Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [et Al.]·Girish S MunavalliRichard Nuccitelli

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