Light and shadows of a new technique: is photon total-skin irradiation using helical IMRT feasible, less complex and as toxic as the electrons one?

Radiation Oncology
Michela BuglioneStefano Maria Magrini

Abstract

Radiotherapy is one of the standard treatments for cutaneous lymphoma and Total Skin Electrons Beam Irradiation (TSEBI) is generally used to treat diffuse cutaneous lymphoma and some cases of localized disease. Helical IMRT (HI) allows to treat complex target with optimal dose distribution and organ at risk sparing, so helical tomotherapy has been proposed as alternative technique to TSEBI but only one preliminary report has been published. Three patients treated (from May 2013 to December 2014) with Helical IMRT, with a total dose between 24 and 30 Gy, were retrospectively evaluated. Data about dosimetric features, response and acute toxicity were registered and analyzed. Planned target coverage was compared with daily in vivo measures and dose calculation based on volumetric images used for set up evaluation as well. The patients had a mean measured surface fraction dose ranging from 1.54 Gy up to 2.0 Gy. A planned target dose ranging from 85 to 120% of prescription doses was obtained. All doses to Organs At Risk were within the required constraints. Particular attention was posed on "whole bone marrow" planned V10Gy, V12Gy and V20Gy values, ranging respectively between 23 and 43%, 20.1 and 38% and 9.8 and 24%. A comparison w...Continue Reading

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Citations

Apr 30, 2019·Journal of Applied Clinical Medical Physics·André HaraldssonPer E Engström
Nov 11, 2019·BMC Veterinary Research·Michael A DeveauAlison B Diesel
Nov 26, 2020·Journal of Clinical Medicine·Yu-Fang LinChen-Hsi Hsieh
Aug 14, 2019·Clinical Oncology : a Journal of the Royal College of Radiologists·L Specht, L Skov

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