PMID: 3750848Jan 1, 1986Paper

Light induced sodium dependent accumulation of calcium and potassium in the extracellular space of bee retina

Vision Research
B Minke, M Tsacopoulos

Abstract

Intense illumination of long duration induced a large transient increase in extracellular calcium (delta[Ca2+]o) and potassium (delta[K+]o) during and after light in bee retina when measured with ion-selective microelectrodes. Whenever a large delta[Ca2+]o appeared, it was accompanied by a transient afterdepolarization (TA). Both the increase in [Ca2+]o, [K+]o and the TA were reduced or abolished when sodium was replaced by arginine, choline or lithium (Li+) ions. At 0-Na conditions a Na independent decrease in [Ca2+]o was observed during illumination only. A pronounced transient depolarization of the photoreceptor in the dark due to transient anoxia did not result in a significant change in [Ca2+]o. In some retinae the elevated level of [K+]o after light was absent, however a small Na-dependent TA was still observed. The above findings suggest that intense long illumination induces a large Ca2+ influx into the photoreceptors which is followed by Na-dependent Ca2+ efflux due to Na-Ca exchange. The light-induced afterdepolarization arises mainly from K+ accumulation in the extracellular space but partially from the electrogenicity of Na-Ca exchange.

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Citations

Apr 1, 1996·Molecular Neurobiology·B Minke, Z Selinger
Mar 20, 2001·Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology·K Azuma
Mar 1, 1994·The Journal of General Physiology·R C Hardie, B Minke
Mar 1, 1989·The Journal of General Physiology·P M O'Day, M P Gray-Keller
May 1, 1990·The Journal of General Physiology·P Hochstrate, K Hamdorf
Feb 1, 1991·The Journal of General Physiology·P M O'DayM Lonergan
Jan 1, 1991·Annals of the New York Academy of Sciences·P M O'Day
Jul 19, 2000·Proceedings of the National Academy of Sciences of the United States of America·J Oberwinkler, D G Stavenga
Aug 4, 2007·Progress in Neurobiology·Tamás L Török
Mar 10, 1999·The American Journal of Physiology·P J BauerJ E Brown
Jul 3, 1999·Physiological Reviews·M P Blaustein, W J Lederer

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