Lights and Shadows about the Effectiveness of IVF in HIV Infected Women: A Systematic Review

Infectious Diseases in Obstetrics and Gynecology
Catarina MarquesSérgio Reis Soares

Abstract

Background. HIV infected women have higher rates of infertility. Objective. The purpose of this literature review is to evaluate the effectiveness of fresh IVF/ICSI cycles in HIV infected women. Materials and Methods. A search of the PubMed database was performed to identify studies assessing fresh nondonor oocyte IVF/ICSI cycle outcomes of serodiscordant couples with an HIV infected female partner. Results and Discussion. Ten studies met the inclusion criteria. Whenever a comparison with a control group was available, with the exception of one case, ovarian stimulation cancelation rate was higher and pregnancy rate (PR) was lower in HIV infected women. However, statistically significant differences in both rates were only seen in one and two studies, respectively. A number of noncontrolled sources of bias for IVF outcome were identified. This fact, added to the small size of samples studied and heterogeneity in study design and methodology, still hampers the performance of a meta-analysis on the issue. Conclusion. Prospective matched case-control studies are necessary for the understanding of the specific effects of HIV infection on ovarian response and ART outcome.

References

Nov 14, 2000·Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America·J D Sobel
Jul 9, 2002·Human Reproduction Update·Egbert R te Velde, Peter L Pearson
May 30, 2003·Human Reproduction·Jeanine OhlIsraël Nisand
Apr 10, 2004·Human Reproduction Update·Yvon EnglertAnne Delbaere
Jun 28, 2005·Human Reproduction·P TerriouR Roulier
Aug 5, 2006·Human Reproduction·Y ManigartA Delvigne
Aug 8, 2006·Human Reproduction Update·F J BroekmansC B Lambalk
Nov 6, 2007·Fertility and Sterility·David B SeiferDavid A Grainger
Dec 17, 2008·AIDS Patient Care and STDs·Nancy Crum-CianfloneAnuradha Ganesan
Dec 17, 2008·Fertility and Sterility·Victor Y FujimotoUNKNOWN Society for Assisted Reproductive Technology Writing Group
Apr 17, 2009·Fertility and Sterility·David B SeiferUNKNOWN Society for Assisted Reproductive Technology Writing Group Report
Apr 22, 2009·Human Reproduction Update·P DevroeyUNKNOWN Evian Annual Reproduction (EVAR) Workshop Group 2008
Jun 27, 2009·AIDS Education and Prevention : Official Publication of the International Society for AIDS Education·Nancy R Reynolds
Jul 23, 2009·Annals of Internal Medicine·David MoherUNKNOWN PRISMA Group
Aug 29, 2009·Reproductive Biomedicine Online·Nataki C DouglasMark V Sauer
Nov 27, 2009·Fertility and Sterility·Samantha F Butts, David B Seifer
May 1, 2010·Gynécologie, obstétrique & fertilité·J OhlJ-M Lang
Aug 6, 2010·Human Reproduction Update·C DechanetH Dechaud
Oct 26, 2010·Fertility and Sterility·Pietro SantulliDominique de Ziegler
Nov 17, 2010·Clinics in Perinatology·Athena P Kourtis, Marc Bulterys
Mar 31, 2011·AIDS Patient Care and STDs·Kathleen E SquiresJudith A Aberg
Apr 5, 2011·American Journal of Obstetrics and Gynecology·Margaret A LampeSteven R Nesheim
Sep 3, 2011·Reproductive Biomedicine Online·Vivian RittenbergTarek El-Toukhy
Sep 11, 2012·Fertility and Sterility·UNKNOWN Practice Committee of the American Society for Reproductive Medicine
Nov 14, 2012·Human Reproduction Update·V SavasiI Cetin
Feb 27, 2013·Journal of Women's Health·Sahadat K NurudeenNataki C Douglas

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Citations

Feb 18, 2017·American Journal of Obstetrics and Gynecology·Brent M Hanson, Jessie A Dorais
Jul 1, 2020·Obstetrical & Gynecological Survey·Elizabeth P HowellKelly S Acharya
Jun 25, 2021·Human Fertility : Journal of the British Fertility Society·Jutharat AttawetElizabeth Sullivan

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