Lignans and Terpenoids from the Leaves of Schisandra chinensis

Chemistry & Biodiversity
Bing-You YangHai-Xue Kuang

Abstract

Fifteen constituents, include one new lignan (schisandroside E, 1) and one new terpenoid (schisandenoid A, 2) as well as nine known lignans and four known terpenoids, were isolated from Schisandra chinensis leaves. The structures of compounds 1-2 were established by entirely meticulous spectroscopic analysis (NMR, MS, CD, IR and UV). All compounds were tested for cytotoxicity against MGC-803, Caco-2 and Ishikawa cell lines. Some compounds showed strong cytotoxicity against these three cancer cell lines with IC50﹤1 μM.

References

Dec 30, 1998·Journal of Natural Products·W J SyuC M Sun
Jan 26, 2002·Journal of Natural Products·Yueh-Hsiung KuoYun-Lian Lin
Oct 26, 2007·Archives of Pharmacal Research·Min Cheol YangKang Ro Lee
May 12, 2010·Planta medica·Karel SmejkalMarie Urbanová
Sep 4, 2015·Chemical & Pharmaceutical Bulletin·Hye Mi KimDae Sik Jang
Mar 26, 2016·Phytochemistry·Turibio Kuiate TabopdaMarie-Aleth Lacaille-Dubois
Nov 11, 2017·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Fenghua LiJie Kang
Nov 16, 2017·Biomedicine & Pharmacotherapy = Biomédecine & Pharmacothérapie·Kandhasamy SowndhararajanSongmun Kim
Jul 6, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Feng QiuXin-Xiang Lei
Nov 17, 2019·Seminars in Immunopathology·F RuizC Pot

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