Lignin-Based Pesticide Delivery System

ACS Omega
Renate WeissGibson S Nyanhongo

Abstract

The potential of lignosulfonates as widely underutilized byproducts of the pulp and paper industry for the synthesis of a biodegradable pesticide carrier system was assessed in this study. Design of experiment software MODDE Pro was for the first time applied to optimize lignosulfonate granule production using Myceliophthora thermophila laccase as a biocatalyst. Enzymatic cross-linking was monitored using size exclusion chromatography coupled online to multiangle laser light scattering, viscosity measurement, and enzyme activity. The determined optimal and experimentally confirmed incubation conditions were: 33 °C, 30 cm3/min O2 supply, and 190 min reaction time. The granules were thereafter loaded with 2 g/kg 3,6-dichloro-2-methoxybenzoic acid (Dicamba), a broad-spectrum herbicide. According to the HPLC analysis, complete release of Dicamba was achieved after 48 h of release. This study showed the green production of a 100% lignosulfonate-based biodegradable solid carrier with potential application in agriculture.

References

Apr 1, 2006·Trends in Biotechnology·Sergio Riva
Nov 21, 2008·Microbial Cell Factories·Adinarayana KunamneniMiguel Alcalde
Apr 11, 2009·Biotechnology Letters·Kristiina HildénTaina Lundell
Jul 25, 2012·Proceedings of the National Academy of Sciences of the United States of America·Prabhu L Pingali
Sep 21, 2016·Applied Microbiology and Biotechnology·Mark D Cannatelli, Arthur J Ragauskas
Sep 17, 2017·The Science of the Total Environment·Martina HvězdováJakub Hofman
Sep 25, 2017·The Science of the Total Environment·Jiao ChenMingzhu Liu
Mar 15, 2018·Molecules : a Journal of Synthetic Chemistry and Natural Product Chemistry·Stefan BeislAnton Friedl
Aug 16, 2019·Food Chemistry·Warren A JohnMatthias S Ullrich

❮ Previous
Next ❯

Citations

Aug 3, 2021·Frontiers in Bioengineering and Biotechnology·Sebastian A MayrGibson S Nyanhongo
Sep 2, 2021·The Science of the Total Environment·Sudisha JogaiahMuthusamy Govarthanan

❮ Previous
Next ❯

Methods Mentioned

BETA
size exclusion chromatography
electron microscopy

Software Mentioned

ASTRA
MODDE
Agilent Openlab Chemstation CDS
MODDE Pro

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.

Related Papers

Clinical Toxicology : the Official Journal of the American Academy of Clinical Toxicology and European Association of Poisons Centres and Clinical Toxicologists
J M Moon, B J Chun
Journal of Industrial Microbiology
A M Fogarty, O H Tuovinen
Fundamental and Applied Toxicology : Official Journal of the Society of Toxicology
P EspandiariL W Robertson
© 2021 Meta ULC. All rights reserved