PMID: 7547030Sep 1, 1995Paper

Like father like son? Sons of patients of European or Indian origin with coronary artery disease reflect their parents' risk factor patterns

British Heart Journal
N ShaukatD R Jones

Abstract

To investigate the extent to which risk factor patterns associated with coronary artery disease (CAD) in patients of Indian origin and in those of North European origin undergoing coronary angiography for suspected angina were reflected in their apparently healthy sons aged 15-30 years. Prospective study in which risk markers were measured in patients of Indian origin and in matched European patients undergoing angiography and in their sons. Patients attending a regional cardiac centre and their families. 102 consecutive male patients of Indian origin undergoing diagnostic coronary angiography for suspected angina and 89 of their sons aged between 15 and 30 years; 102 age matched male European patients and 82 sons. Father son correlations for risk markers predicting the severity of parental CAD; differences in mean levels of these markers between young males of Indian origin and those of North European origin. Lp(a) lipoprotein, total cholesterol, and serum insulin were independent predictors of the severity of CAD in patients of Indian origin and in those of North European origin. In both groups, there was strong correlation between paternal and filial serum insulin (r = 0.41 Indian origin, r = 0.49 North European, P < 0.001),...Continue Reading

References

Aug 16, 1976·Clinica Chimica Acta; International Journal of Clinical Chemistry·P N DurringtonM Hartog
Jul 1, 1978·Progress in Cardiovascular Diseases·W L ProudfitF M Sones
Dec 1, 1992·Arteriosclerosis and Thrombosis : a Journal of Vascular Biology·P CasassusE Eschwège
May 1, 1992·Diabetologia·S RobinsonC Osmond
Aug 26, 1989·BMJ : British Medical Journal·L O HughesE B Raftery
Jan 1, 1986·Diabetes/metabolism Reviews·V A KoivistoR A DeFronzo
Dec 1, 1984·British Heart Journal·P J LowryW A Littler

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Citations

May 4, 2002·American Journal of Preventive Medicine·Kevin E KipPamela J Schreiner
Jul 21, 2010·International Journal of Obesity : Journal of the International Association for the Study of Obesity·A Misra, L Khurana
Feb 7, 2008·International Journal of Cardiology·Konstantinos TziomalosAlexander M Seifalian
Aug 2, 2001·Journal of Investigative Medicine : the Official Publication of the American Federation for Clinical Research·A M ValdesD J Rader
Feb 16, 2007·European Journal of Cardiovascular Prevention and Rehabilitation : Official Journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology·Kerstin A DudasAnnika Rosengren
Feb 20, 1998·The Medical Journal of Australia·J F LynchD E Wilcken

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