Limb flexion-induced axial compression and bending in human femoropopliteal artery segments

Journal of Vascular Surgery
William PoulsonJason N MacTaggart

Abstract

High failure rates of femoropopliteal artery (FPA) interventions are often attributed in part to severe mechanical deformations that occur with limb movement. Axial compression and bending of the FPA likely play significant roles in FPA disease development and reconstruction failure, but these deformations are poorly characterized. The goal of this study was to quantify axial compression and bending of human FPAs that are placed in positions commonly assumed during the normal course of daily activities. Retrievable nitinol markers were deployed using a custom-made catheter system into 28 in situ FPAs of 14 human cadavers. Contrast-enhanced, thin-section computed tomography images were acquired with each limb in the standing (180 degrees), walking (110 degrees), sitting (90 degrees), and gardening (60 degrees) postures. Image segmentation and analysis allowed relative comparison of spatial locations of each intra-arterial marker to determine axial compression and bending using the arterial centerlines. Axial compression in the popliteal artery (PA) was greater than in the proximal superficial femoral artery (SFA) or the adductor hiatus (AH) segments in all postures (P = .02). Average compression in the SFA, AH, and PA ranged fro...Continue Reading

Citations

Feb 23, 2018·Annals of Biomedical Engineering·Kaspars MaleckisAlexey Kamenskiy
Oct 3, 2019·Expert Review of Cardiovascular Therapy·Stefanos Giannopoulos, Ehrin J Armstrong
Aug 18, 2017·Biomechanics and Modeling in Mechanobiology·Anastasia DesyatovaAlexey Kamenskiy
Sep 24, 2020·Revista do Colégio Brasileiro de Cirurgiões·Marcelo DE Azevedo DaherPedro Vaz Duarte
Jun 15, 2019·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Giovanni SpinellaMichele Conti
Sep 19, 2019·Vascular and Endovascular Surgery·Luca GarriboliAntonio Maria Jannello
Mar 27, 2018·Annals of Surgery·Jason MacTaggartAlexey Kamenskiy
Jun 22, 2020·Cardiovascular Revascularization Medicine : Including Molecular Interventions·Stefanos GiannopoulosEhrin J Armstrong
May 19, 2021·Journal of Endovascular Therapy : an Official Journal of the International Society of Endovascular Specialists·Stefanos GiannopoulosEhrin J Armstrong
Jul 14, 2021·European Journal of Applied Physiology·Pierre RamondouPierre Abraham
Jul 17, 2021·VASA. Zeitschrift für Gefässkrankheiten·Ingo HermannMartin Sigl

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