Limitations of Elastography Based Prostate Biopsy

The Journal of Urology
Jonas SchiffmannLukas Manka

Abstract

The role of elastography in patients initially and at repeat prostate biopsy is still indeterminate. The existing literature is sparse and controversial. We studied patients who underwent elastography based and systematic biopsy between October 2009 and February 2015 at Braunschweig Prostate Cancer Center. Patients were separated according to first vs repeat biopsy setting. Each prostate sextant was considered an individual case. The sensitivity, specificity, positive and negative predictive values, and accuracy of elastography to predict biopsy results were analyzed. The 95% CIs were determined by bootstrapping analysis of 2,000 samples. Overall 679 men and a total of 4,074 sextants were identified. Of the 679 men 160 (23.6%) underwent first biopsy and 519 (76.4%) underwent repeat biopsy. In the 160 men at first biopsy sensitivity was 18.0% (95% CI 14.5-21.3), specificity was 87.7% (95% CI 85.3-89.9), positive predictive value was 36.6% (95% CI 28.4-45.4), negative predictive value was 73.0% (95% CI 67.5-77.9) and accuracy was 67.9% (95% CI 63.4-72.2). Results in 519 men (76.4%) at repeat biopsy were 19.8% (95% CI 16.0-23.7), 90.9% (95% CI 89.9-91.9), 20.1% (95% CI 15.8-24.8), 90.7% (95% CI 89.0-92.3) and 83.5% (95% CI 81.6-85...Continue Reading

References

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Citations

Jan 15, 2018·World Journal of Urology·Jeannette KratzenbergKatharina Boehm
Jul 3, 2019·Journal of Ultrasound in Medicine : Official Journal of the American Institute of Ultrasound in Medicine·Zhimin DingFajin Dong
Aug 11, 2017·AJR. American Journal of Roentgenology·Sungmin WooSeung Hyup Kim
Dec 23, 2020·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·F RozetA Méjean
Oct 16, 2019·Progrès en urologie : journal de l'Association française d'urologie et de la Société française d'urologie·F RozetA Méjean

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