PMID: 3744606Aug 1, 1986Paper

Limited effect of magnesium sulphate on torsades de pointes ventricular tachycardia

International Journal of Cardiology
L K Toivonen, H Leinonen

Abstract

A patient with thioridazine-induced torsades de pointes ventricular tachycardia treated with magnesium sulphate is presented. Due to incessant recurrence of tachycardias it was possible to observe the time course of the effect of 1 g intravenous doses. Suppression of torsades de pointes lasted at best for no more than 18 min and a maintenance infusion was not effective without overdrive pacing. Magnesium sulphate may have value as first aid therapy for drug-induced torsades de pointes ventricular tachycardia. However, its effect disappears rapidly, and, therefore, should not alone be relied on as prophylactic treatment.

References

Nov 1, 1977·American Heart Journal·M F Ghani, M Rabah
Jun 1, 1981·The American Journal of Cardiology·M M KhanA A Adgey
Feb 1, 1984·The American Journal of Cardiology·D TzivoniS Stern

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Citations

Aug 1, 1992·Clinical Cardiology·J R Purvis, A Movahed
Apr 1, 1991·Cardiovascular Drugs and Therapy·A Keren, D Tzivoni
Apr 18, 1989·The American Journal of Cardiology·D M Roden
Jan 23, 2003·Molecular Aspects of Medicine·Pietro Delva
May 9, 2000·Australian and New Zealand Journal of Medicine·D J Arnold
Jul 1, 1990·Pacing and Clinical Electrophysiology : PACE·A Keren, D Tzivoni
Jan 1, 1993·Progress in Cardiovascular Diseases·M A Arsenian

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