Limited infection upon human exposure to a recombinant raccoon pox vaccine vector

Vaccine
Tonie E RockeJorge E Osorio

Abstract

A laboratory accident resulted in human exposure to a recombinant raccoon poxvirus (RCN) developed as a vaccine vector for antigens of Yersinia pestis for protection of wild rodents (and other animals) against plague. Within 9 days, the patient developed a small blister that healed within 4 weeks. Raccoon poxvirus was cultured from the lesion, and the patient developed antibody to plague antigen (F1) and RCN. This is the first documented case of human exposure to RCN.

References

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Nov 1, 1941·American Journal of Public Health and the Nation's Health·R H Creel

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Citations

Oct 30, 2009·PloS One·Ginny L EmersonDarin S Carroll
Feb 18, 2010·Molecular Therapy : the Journal of the American Society of Gene Therapy·Laura EvginMarianne M Stanford
Dec 14, 2018·Oncotarget·Marine RicordelPhilippe Erbs
Nov 25, 2020·Nature Communications·Megan E GriffithsDaniel G Streicker

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