Limited macular translocation for neovascular maculopathy

Seminars in Ophthalmology
J A HallerEugene de Juan

Abstract

Subfoveal choroidal neovascularization presents one of the most difficult challenges to vision. No treatment option has yet solved the problem of subretinal hemorrhage and fibrovascular scarring causing permanent photoreceptor degeneration and loss. Limited macular translocation provides a surgical approach to this challenge by moving the fovea onto an adjacent area of relatively normal subretinal space and pigment epithelium in a selected group of patients. The choroidal neovascularization, thus, becomes extrafoveal or juxtafoveal and can be treated with focal laser photocoagulation. This article describes the current technique of limited macular translocation and reviews early results. The procedure offers selected patients a chance to retain useful central vision. About 40% of patients at 6 months are able to read and drive (visual acuity >20/100). Complications including retinal detachment, hemorrhage, and macular folds have decreased with experience. Limited macular translocation is a promising approach to neovascular maculopathy, but needs ongoing careful evaluation.

References

Nov 1, 1993·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·R Machemer, U H Steinhorst
Nov 1, 1993·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·R Machemer, U H Steinhorst
May 30, 1998·Seminars in Ophthalmology·M OhjiY Tano
Feb 10, 1999·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·S WolfB Kirchhof
Apr 20, 1999·Graefe's Archive for Clinical and Experimental Ophthalmology = Albrecht Von Graefes Archiv Für Klinische Und Experimentelle Ophthalmologie·C EckardtH G Conrad
Apr 23, 1999·Retina·F FaudeA Reichenbach
Oct 8, 1999·American Journal of Ophthalmology·E de Juan, J F Vander

❮ Previous
Next ❯

Citations

Apr 16, 2002·Acta Ophthalmologica Scandinavica·Peep V Algvere, Stefan Seregard
Mar 22, 2002·Acta Ophthalmologica Scandinavica·Jens Folke KiilgaardMorten la Cour
Oct 1, 2003·Clinical & Experimental Ophthalmology·Claire Y Hooper, Robyn H Guymer

❮ Previous
Next ❯

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.