Limited resection followed by intraoperative seed implantation is comparable to stereotactic body radiotherapy for solitary lung cancer

Cancer
Bhupesh ParasharK S Clifford Chao

Abstract

The objective of this study was to compare the outcomes of patients who underwent wedge resection plus intraoperative brachytherapy versus patients who received stereotactic body radiotherapy (SBRT) for single malignant lung nodules. A retrospective chart review included 55 patients who were treated for single lung nodules, and 47 of those patients who had adequate information were chosen for the current analysis. Twenty-five patients with single malignant lung nodules received SBRT. Twenty-two patients underwent limited surgical resection plus radioactive seed implantation for solitary malignant lung nodules. Univariate statistical analysis demonstrated a significance difference only for age in the 2 groups: The mean age in the radioactive seed group (66.6 years) was statistically significantly different from the mean of the age in the SBRT group (75.9 years; 2-sided P=.04). No significant differences were observed between the 2 groups in terms of local control, distant metastasis, survival, or toxicity. The current results demonstrated comparable efficacy in outcome and toxicity between surgical resection with radioactive seed implantation and SBRT for the treatment of single malignant lung nodules in patients who were not ca...Continue Reading

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Citations

May 11, 2011·American Journal of Clinical Oncology·Bhupesh ParasharK S Clifford Chao
Jun 2, 2015·Clinical Lung Cancer·Guy C JonesAradhana Kaushal
Mar 22, 2015·Revue de pneumologie clinique·C PricopiM Riquet
Oct 5, 2014·European Journal of Cancer : Official Journal for European Organization for Research and Treatment of Cancer (EORTC) [and] European Association for Cancer Research (EACR)·Yukinori MatsuoMasahiro Hiraoka
Oct 17, 2013·Radiotherapy and Oncology : Journal of the European Society for Therapeutic Radiology and Oncology·Francesca SoldàMichael Brada
Jul 24, 2014·International Journal of Radiation Oncology, Biology, Physics·Xiangpeng ZhengFeng-Ming Spring Kong
Sep 18, 2020·Journal of Cancer Research and Clinical Oncology·Mausam A PatelThomas Kim
Dec 29, 2020·Brachytherapy·Bin QiuJunjie Wang

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