Limited significance of repeated long-term radiological and hormonal examination in nonfunctioning adrenal incidentalomas

International Braz J Urol : Official Journal of the Brazilian Society of Urology
Masayuki TasakiYoshihiko Tomita

Abstract

The purposes of the present study were to evaluate growth rate of nonfunctioning adrenal incidentalomas (AIs) and their development to hormonal hypersecretion on follow-up. A retrospective study was conducted from the electronic medical records. A total of 314 patients were diagnosed with adrenal tumors between 2000 and 2016. After excluding patients who had overt adrenal endocrine disorders or whose adrenal tumors were clinically diagnosed as metastatic malignancies, we investigated 108 patients with nonfunctioning AIs including characteristics, the treatment, the way of follow-up and pathology. Fifteen patients received immediate adrenalectomy because of the initial tumor size or patient's preference. Pathological examination revealed malignancy in 2 patients. In the remaining 93 patients, radiological examinations were performed periodically. Tumor enlargement of ≥ 1.0cm was observed in 8.6% of the patients who were followed up as nonfunctioning AIs with a median follow-up period of 61.5 months (range: 4-192). Eleven patients underwent adrenalectomy. On the pathological examinations, all of the tumors, which showed a size increase, were diagnosed as benign tumors. Regarding the followed up patients without adrenalectomy, onl...Continue Reading

References

Jun 1, 1983·Annals of Internal Medicine·P M Copeland
Aug 1, 1995·Endocrine Reviews·R T KloosB Shapiro
Mar 10, 1998·AJR. American Journal of Roentgenology·M KorobkinF Londy
Apr 19, 2000·The Journal of Clinical Endocrinology and Metabolism·R RossiG Lombardi
Feb 28, 2002·Radiology·Elaine M CaoiliKartik I Raghupathi
Oct 9, 2002·European Journal of Endocrinology·Rossella LibèBruno Ambrosi
Sep 11, 2004·Trends in Endocrinology and Metabolism : TEM·A Sahdev, R H Reznek
May 16, 2006·Journal of Endocrinological Investigation·S BovioM Terzolo
Oct 5, 2007·Endocrine-related Cancer·Ioannis IliasKarel Pacak
Mar 13, 2008·The Journal of Clinical Endocrinology and Metabolism·Mohamed B ElaminVictor M Montori
Aug 1, 1995·Trends in Endocrinology and Metabolism : TEM·H Lavoie, A Lacroix
Oct 29, 2008·Journal of Clinical Pathology·P K Singh, H N Buch
Dec 11, 2008·Clinical Endocrinology·E VassilatouI Tzavara
Apr 8, 2011·European Journal of Endocrinology·M TerzoloUNKNOWN Italian Association of Clinical Endocrinologists
Feb 7, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·David AronT J Cawood
Aug 7, 2012·Best Practice & Research. Clinical Endocrinology & Metabolism·Monica De LeoRosario Pivonello
Jul 17, 2014·European Journal of Nuclear Medicine and Molecular Imaging·Jolanta KunikowskaLeszek Królicki

❮ Previous
Next ❯

Citations

Mar 25, 2020·Endocrinology and Metabolism·Giuseppe ReimondoMassimo Terzolo

❮ Previous
Next ❯

Methods Mentioned

BETA
urine collection
biopsy

Related Concepts

Trending Feeds

COVID-19

Coronaviruses encompass a large family of viruses that cause the common cold as well as more serious diseases, such as the ongoing outbreak of coronavirus disease 2019 (COVID-19; formally known as 2019-nCoV). Coronaviruses can spread from animals to humans; symptoms include fever, cough, shortness of breath, and breathing difficulties; in more severe cases, infection can lead to death. This feed covers recent research on COVID-19.

Blastomycosis

Blastomycosis fungal infections spread through inhaling Blastomyces dermatitidis spores. Discover the latest research on blastomycosis fungal infections here.

Nuclear Pore Complex in ALS/FTD

Alterations in nucleocytoplasmic transport, controlled by the nuclear pore complex, may be involved in the pathomechanism underlying multiple neurodegenerative diseases including Amyotrophic Lateral Sclerosis and Frontotemporal Dementia. Here is the latest research on the nuclear pore complex in ALS and FTD.

Applications of Molecular Barcoding

The concept of molecular barcoding is that each original DNA or RNA molecule is attached to a unique sequence barcode. Sequence reads having different barcodes represent different original molecules, while sequence reads having the same barcode are results of PCR duplication from one original molecule. Discover the latest research on molecular barcoding here.

Chronic Fatigue Syndrome

Chronic fatigue syndrome is a disease characterized by unexplained disabling fatigue; the pathology of which is incompletely understood. Discover the latest research on chronic fatigue syndrome here.

Evolution of Pluripotency

Pluripotency refers to the ability of a cell to develop into three primary germ cell layers of the embryo. This feed focuses on the mechanisms that underlie the evolution of pluripotency. Here is the latest research.

Position Effect Variegation

Position Effect Variagation occurs when a gene is inactivated due to its positioning near heterochromatic regions within a chromosome. Discover the latest research on Position Effect Variagation here.

STING Receptor Agonists

Stimulator of IFN genes (STING) are a group of transmembrane proteins that are involved in the induction of type I interferon that is important in the innate immune response. The stimulation of STING has been an active area of research in the treatment of cancer and infectious diseases. Here is the latest research on STING receptor agonists.

Microbicide

Microbicides are products that can be applied to vaginal or rectal mucosal surfaces with the goal of preventing, or at least significantly reducing, the transmission of sexually transmitted infections. Here is the latest research on microbicides.