Limiting Dietary Sugar Improves Pediatric Sinonasal Symptoms and Reduces Inflammation

Journal of Medicinal Food
Ali SawaniJulie L Wei

Abstract

Excessive sugar consumption is associated with many chronic inflammatory diseases in adults. The effects of excessive sugar consumption in children have not been determined. In this study, we hypothesized that sinonasal symptoms and proinflammatory cytokine levels would be related and could be altered through reduction in sugar-sweetened beverage (SSB) consumption. To test this, we conducted a pilot study involving behavior modification and a 2-week follow-up. Seventeen children participants were recruited, and eleven completed the study. The experimental group presented with chronic nasal congestion or rhinorrhea defined by daily symptoms without acute illness for at least 3 months. The control group presented for non-nasal problems. Both groups received counseling to decrease SSB consumption. The Sinus and Nasal Quality of Life (SN-5) Survey was administered, and a blood sample was obtained by venipuncture at baseline and 2 weeks after counseling. Participants kept a 2-week food diary to document sugar intake. Serum lipid profile and inflammatory cytokines were measured. The experimental group reduced daily sugar intake, 46% versus 11% in the control. Baseline SN-5 scores were significantly worse in the experimental group and...Continue Reading

References

Feb 8, 2003·Otolaryngology--head and Neck Surgery : Official Journal of American Academy of Otolaryngology-Head and Neck Surgery·David J Kay, Richard M Rosenfeld
Mar 31, 2004·The American Journal of Clinical Nutrition·George A BrayBarry M Popkin
Jun 11, 2004·Journal of Evaluation in Clinical Practice·Gillian A LancasterPaula R Williamson
Aug 30, 2005·Metabolism: Clinical and Experimental·Michael E Bizeau, Michael J Pagliassotti
Dec 21, 2007·American Journal of Physiology. Regulatory, Integrative and Comparative Physiology·Yongzhong WeiJames R Sowers
Sep 22, 2009·Clinical and Experimental Immunology·G W Canonica, E Compalati
May 7, 2010·Inflammation·Adaliene Versiani Matos FerreiraLeida Maria Botion
May 14, 2010·International Journal of General Medicine·Robert M NaclerioJames N Baraniuk
Jan 12, 2011·Annual Review of Immunology·Margaret F Gregor, Gökhan S Hotamisligil
Dec 22, 2012·The Journal of Clinical Investigation·Mariana Verdelho MachadoAnna Mae Diehl
Jan 29, 2013·Journal of the Academy of Nutrition and Dietetics·Ethan C KosovaAndrew A Bremer
Feb 20, 2013·The Journal of Experimental Medicine·Ari B MolofskyRichard M Locksley
Jul 8, 2015·The Journal of Allergy and Clinical Immunology·Rebecca K VindingHans Bisgaard

❮ Previous
Next ❯

Citations


❮ Previous
Next ❯

Methods Mentioned

BETA
blood draws
blood drawn

Software Mentioned

SPSS

Related Concepts

Related Feeds

Anti-inflammatory Treatments

A drug or substance that reduces inflammation (redness, swelling, and pain) in the body. Anti-inflammatory agents block certain substances in the body that cause inflammation and swelling. Discover the latest research on anti-inflammatory treatments here

Cardiomyopathy

Cardiomyopathy is a disease of the heart muscle, that can lead to muscular or electrical dysfunction of the heart. It is often an irreversible disease that is associated with a poor prognosis. There are different causes and classifications of cardiomyopathies. Here are the latest discoveries pertaining to this disease.