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Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates

bioRxiv

Nov 25, 2019

Tempei SatoHiroshi Asahara

Abstract

The body plan along the anteroposterior axis and regional identities are specified by the spatiotemporal expression of Hox genes. Multistep controls are required for their unique expression patterns; however, the molecular mechanisms behind the tight control of Hox genes are not fully u...read more

Mentioned in this Paper

LIN28A gene
Axial
Axis
mirnlet7 microRNA, human
Biochemical Pathway
Laboratory mice
LIN-28 protein, human
Plasmodium sp. LIN28A
Gene Knockdown Techniques
Study
3
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Lin28a/let-7 Pathway Modulates the Hox Code via Polycomb Regulation during Axial Patterning in Vertebrates

bioRxiv

Nov 25, 2019

Tempei SatoHiroshi Asahara

DOI: 10.1101/854091

Abstract

The body plan along the anteroposterior axis and regional identities are specified by the spatiotemporal expression of Hox genes. Multistep controls are required for their unique expression patterns; however, the molecular mechanisms behind the tight control of Hox genes are not fully u...read more

Mentioned in this Paper

LIN28A gene
Axial
Axis
mirnlet7 microRNA, human
Biochemical Pathway
Laboratory mice
LIN-28 protein, human
Plasmodium sp. LIN28A
Gene Knockdown Techniques
Study
3

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