Line-field parallel swept source MHz OCT for structural and functional retinal imaging

Biomedical Optics Express
Daniel J FechtigRainer Leitgeb

Abstract

We demonstrate three-dimensional structural and functional retinal imaging with line-field parallel swept source imaging (LPSI) at acquisition speeds of up to 1 MHz equivalent A-scan rate with sensitivity better than 93.5 dB at a central wavelength of 840 nm. The results demonstrate competitive sensitivity, speed, image contrast and penetration depth when compared to conventional point scanning OCT. LPSI allows high-speed retinal imaging of function and morphology with commercially available components. We further demonstrate a method that mitigates the effect of the lateral Gaussian intensity distribution across the line focus and demonstrate and discuss the feasibility of high-speed optical angiography for visualization of the retinal microcirculation.

Associated Clinical Trials

Mar 10, 2021·Yuankai Tao, Yuankai Tao

References

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Citations

Oct 21, 2015·Optics Express·Xiaojun YuLinbo Liu
Aug 30, 2016·Biomedical Optics Express·Chih-Hao LiuKirill V Larin
Mar 9, 2017·Biomedical Optics Express·Chih-Hao LiuKirill V Larin
Dec 29, 2016·Journal of Biomedical Optics·Paul M McNamaraMartin J Leahy
Jan 8, 2019·Biomedical Optics Express·L PuyoM Atlan
Mar 21, 2017·Magnetic Resonance in Medicine : Official Journal of the Society of Magnetic Resonance in Medicine·Daeun KimJustin P Haldar
Apr 1, 2020·Optics Express·Arnaud DuboisJonas Ogien
Mar 20, 2018·Biomedical Optics Express·Laurin GinnerRainer A Leitgeb
Mar 9, 2017·Biomedical Optics Express·Thomas Klein, Robert Huber
Mar 16, 2018·Biomedical Optics Express·Zaineb Al-QazwiniNanguang Chen
Jan 18, 2019·Optics Express·Arnaud DuboisAnaïs Barut
Oct 6, 2020·Biomedical Optics Express·Vimal Prabhu PandiyanRamkumar Sabesan
Dec 8, 2020·Biomedical Optics Express·Tom PfeifferRobert Huber
Apr 1, 2020·Photonics Research·Jason JerwickChao Zhou

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